Evanoff Nicholas G, Dengel Donald R, Narasimhan Shanti
Department of Education and Human Development, School of Kinesiology, University of Minnesota, Minneapolis, Minnesota.
Department of Pediatrics, Pediatric Cardiology, University of Minnesota Medical School, Minneapolis, Minnesota.
J Clin Ultrasound. 2020 May;48(4):211-215. doi: 10.1002/jcu.22828. Epub 2020 Mar 16.
Research describing fetal arterial structure and function is lacking within the literature. This study's purpose was to measure intima-media thickness (IMT), compliance and distensibility of 24- to 25-week fetuses' abdominal aortas using conventional ultrasonography from 16 diabetic (DM) and 25 non-diabetic mothers (NDM). We found no significant differences in fetal abdominal aorta IMT (P = .68), diameter distensibility (P = .22), or cross-sectional distensibility (P = .23). However, both fetal abdominal aortic diameter compliance (P = .03) and cross-sectional compliance (P = .005) were greater in DM than in NDM (P = .005). This study demonstrates that it is possible and potentially useful to measure fetal abdominal aorta biometrics and biomechanical characteristics.
文献中缺乏关于胎儿动脉结构和功能的研究描述。本研究的目的是使用传统超声测量16名糖尿病（DM）母亲和25名非糖尿病母亲（NDM）所孕育的24至25周胎儿腹主动脉的内膜中层厚度（IMT）、顺应性和扩张性。我们发现胎儿腹主动脉的IMT（P = 0.68）、直径扩张性（P = 0.22）或横截面积扩张性（P = 0.23）没有显著差异。然而，糖尿病母亲所孕育胎儿的腹主动脉直径顺应性（P = 0.03）和横截面积顺应性（P = 0.005）均高于非糖尿病母亲（P = 0.005）。本研究表明，测量胎儿腹主动脉生物特征和生物力学特征是可行的，且可能具有实用价值。
