Division of Rheumatology, Department of Internal Medicine, School of Medicine, 161932Universidad de Antioquia, Medellin, Antioquia, Colombia.
Rheumatology, Hospital Nacional Guillermo Almenara Irigoyen, EsSalud, Lima, Perú.
Lupus. 2022 Dec;31(14):1691-1705. doi: 10.1177/09612033221122983. Epub 2022 Aug 29.
Systemic lupus erythematosus (SLE) is an autoimmune disorder with significant health disparities, as it disproportionately and more severely affects vulnerable and disadvantaged population groups in the United States and around the world, that is, women, ethnic minorities, individuals living in poverty, less educated, and lacking medical insurance. Both, genetic and non-genetic factors, contribute to these disparities. To overcome these health disparities and reduce poor outcomes among disadvantaged SLE populations, interventions on non-genetic amendable factors, especially on social health determinants, are necessary.
系统性红斑狼疮（SLE）是一种自身免疫性疾病，存在显著的健康差异，因为它不成比例地更严重地影响了美国和世界各地的脆弱和弱势群体，即妇女、少数民族、生活贫困、受教育程度较低和没有医疗保险的人群。遗传和非遗传因素都导致了这些差异。为了克服这些健康差异并减少弱势 SLE 人群的不良结局，需要针对非遗传可改变因素，特别是社会健康决定因素进行干预。
