Synthesis of Copper Nanoclusters and Their Application for Environmental Pollutant Probes: A Review.

Copper nanoclusters (CuNCs) as a new type of probe for environmental contaminants are gaining increasing attention because of its low cost, superior water dispersibility, wide availability and excellent optical properties. Compared with the other probes such as quantum dots and organic dyes, CuNCs show much more potential in practical application for their excellent photostability, large Stokes shift, low toxicity and other preponderance, especially in the fields of biosensing and environmental monitoring. Recently, the template-assisted synthesis of metal nanoclusters (MNCs) has been widely studied. A variety of templates such as proteins, small thiol molecules, polymers, and DNA with different spatial configuration have been used for the preparation of MNCs so far. This review primarily described recent advances in CuNCs in terms of the synthesis of CuNCs from different templates, the methods to improve the fluorescence (FL) properties of CuNCs, as well as the basic detection mechanisms based on the FL properties or catalytic properties. Finally, to promote the practical application of CuNCs probes, the challenges and prospects of CuNCs multifunctional probes are also discussed.