氮掺杂碳点对硫氢化物具有高选择性的传感及其在活细胞中的成像。
Nitrogen-doped carbon dots with high selectivity for hydrosulfide sensing and their living cells imaging.
机构信息
Center for Biomedical Optics and Photonics (CBOP) & College of Physics and Optoelectronic Engineering, Key Lab of Optoelectronics Devices and Systems of Ministry of Education/Guangdong Province, Shenzhen University, Shenzhen, 518060, PR China.
Center for Biomedical Optics and Photonics (CBOP) & College of Physics and Optoelectronic Engineering, Key Lab of Optoelectronics Devices and Systems of Ministry of Education/Guangdong Province, Shenzhen University, Shenzhen, 518060, PR China; National Research Nuclear University MEPhI (Moscow Engineering Physics Institute), 115409, Moscow, Russian Federation.
出版信息
Anal Chim Acta. 2022 Sep 8;1225:340202. doi: 10.1016/j.aca.2022.340202. Epub 2022 Aug 9.
Hydrosulfuric acid is an aqueous solution of hydrogen sulfide (HS). At physiological pH, approximately 80% of the total amount of HS exists in the form of monoanionic HS. Because HS is both widely distributed and highly toxic to humans, it is necessary to design an efficient method to detect HS with high sensitivity and selectivity. So, the nitrogen-doped carbon dots (NCDs) with green fluorescence are synthesized using a one-step hydrothermal method. The as-prepared NCDs show it can be effectively used as an indicator for monitoring HS. And the NCD fluorescence intensity exhibits a linear relationship with HS concentration. In addition, NCDs as a probe can be applied for fluorescence imaging in living cells to detect the presence of trace exogenous HS.
氢硫酸是硫化氢（HS）的水溶液。在生理 pH 值下，大约 80%的 HS 以单阴离子 HS 的形式存在。由于 HS 在人体内分布广泛且毒性很高，因此需要设计一种高效的方法来检测 HS，使其具有高灵敏度和选择性。因此，采用一步水热法合成了具有绿色荧光的氮掺杂碳点（NCDs）。所制备的 NCDs 可有效用作监测 HS 的指示剂。并且 NCD 的荧光强度与 HS 浓度呈线性关系。此外，NCD 作为探针可应用于活细胞中的荧光成像，以检测痕量外源性 HS 的存在。
Zotero 插件