Ren Kehui, Liu Houfang, Li Bingyan, Zhou Bingrong
Department of Dermatology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Department of Dermatology, The Fourth people's Hospital of Zhenjiang, Zhenjiang, China.
J Cosmet Dermatol. 2022 Dec;21(12):6742-6753. doi: 10.1111/jocd.15339. Epub 2022 Sep 20.
This study aimed to analyze the clinical results and influencing factors of the fractional microneedle radiofrequency (FMR) treatment for enlarged facial pores on different facial sites.
The clinical data of patients with enlarged facial pores who underwent FMR treatment from January 2019 to December 2020 were collected. The efficacy and complications of FMR for enlarged pores in different facial areas were retrospectively analyzed. Univariate and multivariate logistic regression analyses were used to explore the clinical factors related to the efficacy of FMR after the first treatment session.
Totally, 75 patients with enlarged facial pores were included (full-face FMR for 45, nasal FMR for 58, frontal FMR for 45, and cheek FMR for 72 patients). All patients received more than one treatment session, two patients received five treatment sessions, and the mean number of FMR session was 1.7. The moderate to excellent improvement rates in patients with nasal, frontal and cheek enlarged pores after the first session were 13.8%, 8.9%, and 11.1%, respectively. The improvement rate rose with the increasing number of treatment sessions. Multivariate logistic regression analysis revealed that long pulse-width (300 ms) was positively associated with clinical efficacy after the first session (OR = 22.4, 95% CI [2.0-250.4], p = 0.012), compared with the short pulse-width group (100-200 ms). The main adverse effects after FMR were transient pain, erythema, and edema. A minority of patients developed acneiform eruption.
This study confirms that FMR is safe and effective in improving enlarged facial pores. The pulse width is associated with the improvement of nasal enlarged pores.
本研究旨在分析分次微针射频（FMR）治疗不同面部部位毛孔粗大的临床效果及影响因素。
收集2019年1月至2020年12月接受FMR治疗的毛孔粗大患者的临床资料。回顾性分析FMR治疗不同面部区域毛孔粗大的疗效及并发症。采用单因素和多因素logistic回归分析探讨首次治疗后与FMR疗效相关的临床因素。
共纳入75例毛孔粗大患者（45例行全脸FMR，58例行鼻部FMR，45例行额部FMR，72例行颊部FMR）。所有患者均接受了不止一次治疗，2例患者接受了5次治疗，FMR治疗的平均次数为1.7次。首次治疗后，鼻部、额部和颊部毛孔粗大患者的中度至优秀改善率分别为13.8%、8.9%和11.1%。改善率随治疗次数的增加而升高。多因素logistic回归分析显示，与短脉宽组（100 - 200毫秒）相比，长脉宽（300毫秒）与首次治疗后的临床疗效呈正相关（OR = 22.4，95%CI[2.0 - 250.4]，p = 0.012）。FMR后的主要不良反应为短暂疼痛、红斑和水肿。少数患者出现痤疮样皮疹。
本研究证实FMR在改善面部毛孔粗大方面安全有效。脉宽与鼻部毛孔粗大的改善有关。
