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住院期间的血糖监测:高级执业护士与半自动胰岛素处方工具

Blood glucose monitoring during hospitalisation: Advanced practice nurse and semi-automated insulin prescription tools.

作者信息

Yago-Esteban Gema, Venturas Montse, Blanco Jesús, Pérez Inma, Falces Carlos, Roqué Mercè, Yugueros Xavier, Cardete Laura, Renu Arturo, Caellas David, Conget Ignacio, Ortega Emilio

机构信息

Servicio de Endocrinología y Nutrición, ICMDM, Hospital Clínic Barcelona, Barcelona, Spain.

Servicio de Cardiología, ICCV, Hospital Clínic Barcelona, Barcelona, Spain.

出版信息

Endocrinol Diabetes Nutr (Engl Ed). 2022 Aug-Sep;69(7):500-508. doi: 10.1016/j.endien.2022.07.008. Epub 2022 Aug 26.

Abstract

INTRODUCTION

Hyperglycemia is very common in hospitalized patients and is associated with worse clinical outcomes.

AIMS

We implemented a clinical and educational program to improve the overall glycemic control during hospital admission, and, in patients with HbA > 8%, to improve their metabolic control after hospital admission.

METHODS

Non-critical patients admitted to cardiovascular areas between October-2017 and February-2019. The program was led by an advanced nurse practitioner (ANP) and included a semiautomated insulin prescription tool. Program in 3 phases: 1) observation of routine practice, 2) implementation, and 3) follow-up after discharge.

RESULTS

During the implementation phase the availability of HbA1c increased from 42 to 81%, and the ANP directly intervened in 73/685 patients (11%), facilitating treatment progression at discharge in 48% (de novo insulin in 36%). One-year after discharge, HbA1c in patients who were admitted during the observation phase with HbA1c > 8% (n = 101) was higher than similar patients admitted during implementation phase (8,6 ± 1,5 vs. 7,3 ± 1,2%, respectively, p < 0,001). We evaluated 47710 point of care capillary blood glucose (POC-glucose) in two 9 months periods (one before, one during the program) in cardiology and cardiovascular surgery wards. POC-glucose ≥250 mg/dl (pre vs. during: cardiology 10,7 vs. 8,4%, and surgery 7,4 vs. 4,5%, both p < 0,05) and <70 mg/dl (2,3 vs. 0,8% y 1,5 vs 1%, p < 0,05), respectively, improved during the program.

CONCLUSIONS

The program allowed improving inpatient glycemic control, detect patients with poor glycemic control, and optimize metabolic control 1-year after discharge.

摘要

引言

高血糖在住院患者中非常常见,且与较差的临床结局相关。

目的

我们实施了一项临床和教育计划,以改善住院期间的总体血糖控制,并在糖化血红蛋白(HbA)>8%的患者中,改善其出院后的代谢控制。

方法

2017年10月至2019年2月期间入住心血管科的非危重症患者。该计划由一名高级执业护士(ANP)牵头,并包括一个半自动胰岛素处方工具。计划分三个阶段:1)常规实践观察,2)实施,3)出院后随访。

结果

在实施阶段,糖化血红蛋白(HbA1c)检测的可及性从42%提高到81%,ANP直接干预了73/685例患者(11%),使48%的患者出院时治疗进展顺利(36%为起始使用胰岛素)。出院一年后,观察阶段入院时HbA1c>8%的患者(n = 101)的HbA1c高于实施阶段入院的类似患者(分别为8.6±1.5 vs. 7.3±1.2%,p<0.001)。我们在心脏病学和心血管外科病房的两个9个月期间(一个在计划前,一个在计划期间)评估了47710次即时护理毛细血管血糖(POC-葡萄糖)。计划期间,POC-葡萄糖≥250mg/dl(心脏病学:计划前vs.计划期间为10.7% vs. 8.4%,外科为7.4% vs. 4.5%,均p<0.05)和<70mg/dl(2.3% vs. 0.8%以及1.5% vs 1%,p<0.05)的情况均有所改善。

结论

该计划有助于改善住院患者的血糖控制,发现血糖控制不佳的患者,并在出院1年后优化代谢控制。

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