延长瑞德西韦输注治疗持续性冠状病毒病2019感染
Extended Remdesivir Infusion for Persistent Coronavirus Disease 2019 Infection.
作者信息
Martinez Mario A, Chen Ting-Yi, Choi Hosoon, Hwang Munok, Navarathna Dhammika, Hao Linhue, Gale Michael, Camus Gregory, Ramirez Hector E, Jinadatha Chetan
机构信息
Division of Infectious Diseases, Baylor Scott and White Health, Temple, Texas, USA.
Department of Medicine, Central Texas Veterans Health Care System, Temple, Texas, USA.
出版信息
Open Forum Infect Dis. 2022 Jul 29;9(8):ofac382. doi: 10.1093/ofid/ofac382. eCollection 2022 Aug.
Persistent severe acute respiratory syndrome coronavirus 2 infection is difficult to treat. Here, we report a case of 5-month persistent coronavirus disease 2019 in an immunocompromised patient who was successfully treated with 30 consecutive days of remdesivir. Prolonged remdesivir infusion with concurrent cycle threshold monitoring might provide a potential solution to cure these patients with difficult-to-treat infections.
持续性严重急性呼吸综合征冠状病毒2感染难以治疗。在此，我们报告一例免疫功能低下患者发生的长达5个月的2019冠状病毒病病例，该患者通过连续30天使用瑞德西韦成功治愈。延长瑞德西韦输注时间并同时进行循环阈值监测可能为治愈这些难治性感染患者提供一种潜在的解决方案。
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