Department of Head and Neck Surgery, Aichi Cancer Center Hospital, Nagoya, Japan.
Department of Otorhinolaryngology, Nagoya University Graduate School of Medicine, Nagoya, Japan.
Anticancer Res. 2022 Sep;42(9):4597-4602. doi: 10.21873/anticanres.15963.
BACKGROUND/AIM: The utility of F-fluorodeoxyglucose positron emission tomography/computed tomography (F-FDG-PET/CT) for clinical T classification of synchronous esophageal cancer (SEC) in pharyngeal cancer has not been fully elucidated. We investigated the association between F-FDG-PET/CT and clinical T classification for SEC.
We retrospectively enrolled 90 patients with pharyngeal cancer having both Lugol chromoendoscopy and F-FDG-PET/CT at pretreatment. The association between F-FDG-PET/CT and pathological examination was compared by the Fisher's exact test.
Pathologically, 12 patients with SEC were diagnosed. The number of locations for SEC with cT1a, cT1b, and cT3 was 20, 1, and 1, respectively. Sensitivity for cT1a-cT3, cT1b-cT3, and cT3 was 9.1%, 100%, and 100%, respectively. Locations of SEC with cT1b-cT3 were significantly detected. The locations of SEC with cT1b-cT3 were more frequently detected than those without cT1b-cT3 by F-FDG-PET/CT (p<0.01).
Detection of SEC with clinical T1b-T3 in comparison to clinical T1a on pretreatment F-FDG-PET/CT for patients with pharyngeal cancer, was achieved with high sensitivity.
背景/目的：氟代脱氧葡萄糖正电子发射断层扫描/计算机断层扫描（F-FDG-PET/CT）在评估同时性食管癌（SEC）中的临床 T 分期的效用尚未得到充分阐明。我们研究了 F-FDG-PET/CT 与 SEC 临床 T 分期之间的关系。
我们回顾性纳入了 90 例接受咽癌治疗前行卢戈氏碘染色和 F-FDG-PET/CT 检查的患者。采用 Fisher 确切检验比较 F-FDG-PET/CT 与病理检查的相关性。
病理诊断 SEC 患者 12 例。SEC 的 cT1a、cT1b 和 cT3 部位数分别为 20、1 和 1。cT1a-cT3、cT1b-cT3 和 cT3 的敏感度分别为 9.1%、100%和 100%。cT1b-cT3 的 SEC 部位明显可被检测到。与 cT1a 相比，cT1b-cT3 的 SEC 部位在 F-FDG-PET/CT 中更常被检测到（p<0.01）。
与临床 T1a 相比，咽癌患者治疗前的 F-FDG-PET/CT 对临床 T1b-T3 的 SEC 检测具有较高的敏感度。
