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[腺嘌呤核苷酸在甲型血友病患者血小板功能活性中的作用]

[The role of adenine nucleotides in the functional activity of platelets in hemophilia A].

作者信息

Mareeva T B, Sokovnina Ia M, Votrin I I

出版信息

Vopr Med Khim. 1987 Mar-Apr;33(2):100-4.

PMID:3604129
Abstract

Content of adenine nucleotides was studied in various pools of thrombocytes from donors and from patients with hemophilia A. Biochemical deficiency of adenine nucleotides appears to occur in the pool of thrombocytes obtained from patients with hemophilia A; estimation of ADP and ATP in the storage granules as well as of the nucleotides specific radioactivity may serve as a criterion of thrombocyte disfunction.

摘要

对来自献血者和甲型血友病患者的不同血小板池中的腺嘌呤核苷酸含量进行了研究。在来自甲型血友病患者的血小板池中似乎出现了腺嘌呤核苷酸的生化缺陷;储存颗粒中ADP和ATP的测定以及核苷酸的比放射性可作为血小板功能障碍的一个标准。

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