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[添加腺嘌呤和鸟苷后储存血液中腺嘌呤核苷酸的行为]

[Behavior of adenine nucleotides in stored blood with addition of adenine and guanosine].

作者信息

Stigge V, Seidel B

出版信息

Acta Biol Med Ger. 1977;36(3-4):549-53.

PMID:596063
Abstract

ACD stored blood was substituted with adenine, guanosine or both during usual storage conditions. In weekly intervals concentrations of ATP, ADP and AMP were estimated. From the obtained values it was suggested that the substitutions of adenine and guanosine probably lead to synthesis of the three measured adenine nucleotides. The apparent additive effect of adenine and guanosine upon ATP concentration probably is caused by the simultaneous measurement of GTP and ATP in the used nonspecific method. Under these conditions GTP would have significance for the survival of erythrocytes stored in ACD-AG-medium.

摘要

在常规储存条件下,用腺嘌呤、鸟苷或两者替代ACD储存血液。每周测定一次ATP、ADP和AMP的浓度。从所得值推测,腺嘌呤和鸟苷的替代可能导致三种被测腺嘌呤核苷酸的合成。腺嘌呤和鸟苷对ATP浓度的明显相加作用可能是由于所用非特异性方法同时测定了GTP和ATP。在这些条件下,GTP对储存在ACD-AG培养基中的红细胞存活具有重要意义。

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Acta Biol Med Ger. 1977;36(3-4):549-53.
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