[大鼠小肠中二肽酶的分布]
[Distribution of dipeptidases in the rat small intestine].
作者信息
Demina T Iu
出版信息
Vopr Med Khim. 1987 Mar-Apr;33(2):104-6.
GlyLeu- and AlaAla-dipeptidase activities were studied in various zones of digestion: in mucosal deposit of small intestine, in epithelium of homogenate free of mucosal deposit and in washing water of small intestine. The highest rate of the dipeptidases activity was found in washing water of small intestine; at the same time, the activity in mucosal deposit exceeded its level in homogenate of small intestine epithelium. The dipeptidases, which are synthesized in small intestine epithelial cells, are apparently accumulated in mucosal deposit and then diffused into intestinal lumen, where the first steps of intestinal digestion occurred, while the most effective intestinal digestion proceeded in mucosal deposit.
对甘氨酰亮氨酸二肽酶和丙氨酰丙氨酸二肽酶的活性在消化的各个区域进行了研究
在小肠的黏膜沉积物中、在不含黏膜沉积物的匀浆上皮中以及在小肠的冲洗液中。发现小肠冲洗液中肽酶活性最高；同时，黏膜沉积物中的活性超过了小肠上皮匀浆中的活性水平。在小肠上皮细胞中合成的肽酶显然在黏膜沉积物中积累，然后扩散到肠腔中，肠道消化的第一步在此发生，而最有效的肠道消化则在黏膜沉积物中进行。
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