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一名Ch阳性患者体内的同种抗奇多(抗体)

Allo-anti-Chido in a Ch-positive patient.

作者信息

Giles C M, Hoffman M, Moulds M, Harris M, Dalmasso A

出版信息

Vox Sang. 1987;52(1-2):129-33. doi: 10.1111/j.1423-0410.1987.tb03008.x.

DOI:10.1111/j.1423-0410.1987.tb03008.x
PMID:3604158
Abstract

Allo-anti-Chido (Ch) was detected in a patient whose red cells typed as Ch+. The C4 allotype of the patient was A4,B2 which associates strongly with the Ch phenotype Ch:1,-2,3,4,-5,6. Anti-Ch2 + Ch5 were the Ch specificities identified. Absence of only Ch2 and Ch5 determinants on the C4B protein allowed this unique immune response to blood transfusion.

摘要

在一名红细胞血型为Ch+的患者中检测到同种抗奇多(Ch)。该患者的C4同种异型为A4、B2,与Ch表型Ch:1,-2,3,4,-5,6密切相关。鉴定出的Ch特异性抗体为抗Ch2 + Ch5。C4B蛋白上仅缺乏Ch2和Ch5决定簇,导致了这种独特的输血免疫反应。

相似文献

1
Allo-anti-Chido in a Ch-positive patient.一名Ch阳性患者体内的同种抗奇多(抗体)
Vox Sang. 1987;52(1-2):129-33. doi: 10.1111/j.1423-0410.1987.tb03008.x.
2
Three Chido determinants detected on the B5Rg+ allotype of human C4: their expression in Ch-typed donors and families.
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Rodgers (Rg) and Chido (Ch) determinants on human C4: characterization of two C4 B5 subtypes, one of which contains Rg and Ch determinants.人类C4上的罗德格斯(Rg)和奇多(Ch)决定簇:两种C4 B5亚型的特征,其中一种含有Rg和Ch决定簇。
J Immunol. 1984 Nov;133(5):2634-40.
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Antigenic determinants expressed by human C4 allotypes; a study of 325 families provides evidence for the structural antigenic model.人类补体C4同种异型所表达的抗原决定簇;对325个家族的研究为结构抗原模型提供了证据。
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An international reference typing for Ch and Rg determinants on rare human C4 allotypes.
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C4B3 allotype with a novel Ch phenotype.具有新型Ch表型的C4B3同种异型
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C4 and HLA haplotypes associated with partial inhibition of anti-Rg and anti-Ch.与抗Rg和抗Ch部分抑制相关的C4和HLA单倍型
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Association between the electrophoretically-determined C4M haplotype product and partial inhibition of anti-Cha.电泳测定的C4M单倍型产物与抗ChA部分抑制之间的关联。
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A structural model for the location of the Rodgers and the Chido antigenic determinants and their correlation with the human complement component C4A/C4B isotypes.罗杰斯和奇多抗原决定簇定位及其与人类补体成分C4A/C4B同种型相关性的结构模型。
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引用本文的文献

1
The study of a French family with two duplicated C4A haplotypes.对一个拥有两个重复的C4A单倍型的法国家庭的研究。
Hum Genet. 1987 Dec;77(4):359-65. doi: 10.1007/BF00291427.
2
Antigenic determinants expressed by human C4 allotypes; a study of 325 families provides evidence for the structural antigenic model.人类补体C4同种异型所表达的抗原决定簇;对325个家族的研究为结构抗原模型提供了证据。
Immunogenetics. 1988;27(6):442-8. doi: 10.1007/BF00364431.
3
A structural model for the location of the Rodgers and the Chido antigenic determinants and their correlation with the human complement component C4A/C4B isotypes.
罗杰斯和奇多抗原决定簇定位及其与人类补体成分C4A/C4B同种型相关性的结构模型。
Immunogenetics. 1988;27(6):399-405. doi: 10.1007/BF00364425.