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Studies on the mechanism of human red cell loss of viability during storage at +4 degrees C. II. Relation between cellular morphology and viability.

作者信息

Högman C F, de Verdier C H, Borgström L

出版信息

Vox Sang. 1987;52(1-2):20-3.

PMID:3604164
Abstract

Red cells collected in CPD, suspended in SAGM solution and stored for 42 days at +4 degrees C, were tested before and after incubation for 1 h at 37 degrees C with respect to autologous 24-hour posttransfusion red cell survival, morphology, fluidity at low shear rate and adenylate content. Warming and to some extent chromium labelling of the cells resulted in improvement of the morphology and fluidity but in no increase in adenosine triphosphate, total adenylate concentration or posttransfusion survival. The conclusion is drawn that short-term improvement of the morphology before transfusion does not result in increased viability.

摘要

相似文献

1
Studies on the mechanism of human red cell loss of viability during storage at +4 degrees C. II. Relation between cellular morphology and viability.
Vox Sang. 1987;52(1-2):20-3.
2
Cell shape and total adenylate concentration as important factors for posttransfusion survival of erythrocytes.细胞形状和总腺苷酸浓度是影响红细胞输血后存活的重要因素。
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Storage of red cell concentrates in CPD-A2 for 42 and 49 days.红细胞浓缩液在CPD - A2中储存42天和49天。
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Preservation of red blood cells with purines and nucleosides. I. Changes of ATP, 2,3-P2G and further parameters of metabolism in red cells stored as whole blood and as resuspension at 4 degrees C and 25 degrees C.用嘌呤和核苷保存红细胞。I. 全血储存以及在4℃和25℃下重悬保存的红细胞中ATP、2,3-二磷酸甘油酸及其他代谢参数的变化
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[Viability, ATP and 2,3-DPG content of resuspended erythrocytes during several-week storage in cold].[冷藏数周期间重悬红细胞的活力、ATP及2,3-二磷酸甘油酸含量]
Acta Biol Med Ger. 1977;36(3-4):543-8.

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2
Time-related shape control modifications during erythrocyte storage with additive solutions.
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