Department of Cardiology, Copenhagen University Hospital - Herlev and Gentofte, Hellerup, Denmark.
Multidisciplinary Center, Federal University of Acre, Câmpus Floresta, Cruzeiro do Sul, Acre, Brazil.
BMJ Open. 2022 Aug 30;12(8):e058277. doi: 10.1136/bmjopen-2021-058277.
Prior studies have suggested that self-rated health may be a useful indicator of cardiovascular disease. Consequently, we aimed to assess the relationship between self-rated health, cardiovascular risk factors and subclinical cardiac disease in the Amazon Basin.
Cross-sectional study.
SETTING, PARTICIPANTS AND INTERVENTIONS: In participants from the Amazon Basin of Brazil we obtained self-rated health according to a Visual Analogue Scale, ranging from 0 (poor) to 100 (excellent). We performed questionnaires, physical examination and echocardiography. Logistic and linear regression models were applied to assess self-rated health, cardiac risk factors and cardiac disease by echocardiography. Multivariable models were mutually adjusted for other cardiovascular risk factors, clinical and socioeconomic data, and known cardiac disease.
Cardiovascular risk factors and subclincial cardiac disease by echocardiography.
A total of 574 participants (mean age 41 years, 61% female) provided information on self-rated health (mean 75±21 (IQR 60-90) points). Self-rated health (per 10-point increase) was negatively associated with hypertension (OR 0.87 (95% CI 0.78 to 0.97), p=0.01), hypercholesterolaemia (OR 0.89 (95%CI 0.80 to 0.99), p=0.04) and positively with healthy diet (OR 1.13 (95%CI 1.04 to 1.24), p=0.004). Sex modified these associations (p-interaction <0.05) such that higher self-rated health was associated with healthy diet and physical activity in men, and lower odds of hypertension and hypercholesterolaemia in women. No relationship was found with left ventricular ejection fraction <45% (OR 0.97 (95% CI 0.77 to 1.23), p=0.8), left ventricular hypertrophy (OR 0.97 (95% CI 0.76 to 1.24), p=0.81) or diastolic dysfunction (OR 1.09 (95% CI 0.85 to 1.40), p=0.51).
Self-rated health was positively associated with health parameters in the Amazon Basin, but not with subclinical cardiac disease by echocardiography. Our findings are of hypothesis generating nature and future studies should aim to determine whether assessment of self-rated health may be useful for screening related to policy-making or lifestyle interventions.
Clinicaltrials.gov: NCT04445103; Post-results.
先前的研究表明，自我评估的健康状况可能是心血管疾病的一个有用指标。因此，我们旨在评估亚马逊流域自我评估的健康状况、心血管风险因素和亚临床心脏疾病之间的关系。
横断面研究。
地点、参与者和干预措施：在来自巴西亚马逊流域的参与者中，我们根据视觉模拟量表（范围从 0[差]到 100[优]）获得自我评估的健康状况。我们进行了问卷调查、体格检查和超声心动图检查。应用逻辑回归和线性回归模型评估自我评估的健康状况、心血管风险因素和超声心动图检查的心脏疾病。多变量模型相互调整了其他心血管风险因素、临床和社会经济数据以及已知的心脏疾病。
心血管风险因素和超声心动图检查的亚临床心脏疾病。
共有 574 名参与者（平均年龄 41 岁，61%为女性）提供了自我评估健康状况（平均 75±21（IQR 60-90）分）的信息。自我评估健康状况（每增加 10 分）与高血压（比值比 0.87（95%置信区间 0.78 至 0.97），p=0.01）、高胆固醇血症（比值比 0.89（95%置信区间 0.80 至 0.99），p=0.04）呈负相关，与健康饮食呈正相关（比值比 1.13（95%置信区间 1.04 至 1.24），p=0.004）。性别改变了这些关联（p 交互<0.05），即自我评估健康状况较高与男性的健康饮食和体育活动有关，与女性的高血压和高胆固醇血症的可能性降低有关。与左心室射血分数<45%（比值比 0.97（95%置信区间 0.77 至 1.23），p=0.8）、左心室肥厚（比值比 0.97（95%置信区间 0.76 至 1.24），p=0.81）或舒张功能障碍（比值比 1.09（95%置信区间 0.85 至 1.40），p=0.51）无相关性。
自我评估的健康状况与亚马逊流域的健康参数呈正相关，但与超声心动图检查的亚临床心脏疾病无关。我们的研究结果具有假设产生的性质，未来的研究应旨在确定评估自我评估的健康状况是否可用于与政策制定或生活方式干预相关的筛查。
Clinicaltrials.gov：NCT04445103；Post-results。
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