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老年科学的资金渠道。

The Funding Channels of Geroscience.

作者信息

Lederman Stephanie

机构信息

Executive Director, American Federation for Aging Research (AFAR), New York, New York 10018, USA.

出版信息

Cold Spring Harb Perspect Med. 2023 Jan 3;13(1):a041210. doi: 10.1101/cshperspect.a041210.

Abstract

This review examines the interconnected channels of government, individual, and corporate funding for geroscience. A sometimes-slow flow of federal and philanthropic funding over 50 years is now becoming sufficient to understand how the processes of aging drive disease. The amount has not yet been enough to push the benefits of geroscience into new therapeutics, but that is poised to change. Prominent billionaires, venture capitalists, and new foundations are investing billions in researching approaches for preventing, delaying, or curing the chronic diseases of older people; major pharmaceutical companies are poised to join them once the Food and Drug Administration qualifies aging as a treatable condition. The coming decade could see considerable progress, not only in the science but also in the creation of fresh nonprofit and for-profit funding streams.

摘要

本综述探讨了政府、个人和企业为老年科学提供资金的相互关联渠道。50年来,联邦和慈善资金的流动有时较为缓慢,如今已足以了解衰老过程如何引发疾病。这笔资金数额尚未足以将老年科学的益处转化为新的治疗方法,但这种情况即将改变。知名亿万富翁、风险投资家以及新成立的基金会正投入数十亿美元,用于研究预防、延缓或治愈老年人慢性病的方法;一旦美国食品药品监督管理局将衰老认定为一种可治疗的病症,各大制药公司也准备加入其中。未来十年,不仅在科学方面,而且在创建新的非营利性和营利性资金流方面都可能取得显著进展。

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本文引用的文献

1
The economic value of targeting aging.靶向衰老的经济价值。
Nat Aging. 2021 Jul;1(7):616-623. doi: 10.1038/s43587-021-00080-0. Epub 2021 Jul 5.
2
Can we make drug discovery targeting fundamental mechanisms of aging a reality?我们能否将针对衰老基本机制的药物研发变为现实?
Expert Opin Drug Discov. 2022 Feb;17(2):97-100. doi: 10.1080/17460441.2022.1993818. Epub 2021 Oct 22.
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John A. Hartford Foundation Centers of Excellence Program: History, Impact, and Legacy.
J Am Geriatr Soc. 2017 Jul;65(7):1396-1400. doi: 10.1111/jgs.14852. Epub 2017 Mar 17.

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