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1
Author Correction: PHGDH heterogeneity potentiates cancer cell dissemination and metastasis.作者更正：磷酸甘油酸脱氢酶（PHGDH）的异质性增强癌细胞的播散和转移。
Nature. 2022 Sep;609(7927):E8. doi: 10.1038/s41586-022-05226-7.
2
Knockdown of PHGDH potentiates 5-FU cytotoxicity in gastric cancer cells via the Bcl-2/Bax/caspase-3 signaling pathway.敲低PHGDH通过Bcl-2/Bax/半胱天冬酶-3信号通路增强5-氟尿嘧啶对胃癌细胞的细胞毒性。
Int J Clin Exp Pathol. 2018 Dec 1;11(12):5869-5876. eCollection 2018.
3
PHGDH is an independent prognosis marker and contributes cell proliferation, migration and invasion in human pancreatic cancer.磷酸甘油酸脱氢酶（PHGDH）是一种独立的预后标志物，在人类胰腺癌中促进细胞增殖、迁移和侵袭。
Gene. 2018 Feb 5;642:43-50. doi: 10.1016/j.gene.2017.11.014. Epub 2017 Nov 8.
4
High Expression of PHGDH Predicts Poor Prognosis in Non-Small Cell Lung Cancer.磷酸甘油酸脱氢酶高表达预示非小细胞肺癌预后不良。
Transl Oncol. 2016 Dec;9(6):592-599. doi: 10.1016/j.tranon.2016.08.003.
5
Phosphoglycerate dehydrogenase is a novel predictor for poor prognosis in gastric cancer.磷酸甘油酸脱氢酶是胃癌预后不良的一种新的预测指标。
Onco Targets Ther. 2016 Sep 7;9:5553-60. doi: 10.2147/OTT.S105787. eCollection 2016.
6
Correction: PHGDH Expression Is Required for Mitochondrial Redox Homeostasis, Breast Cancer Stem Cell Maintenance, and Lung Metastasis.更正：PHGDH表达是线粒体氧化还原稳态、乳腺癌干细胞维持和肺转移所必需的。
Cancer Res. 2022 Mar 15;82(6):1153. doi: 10.1158/0008-5472.CAN-21-4328.
7
PHGDH as a mechanism for resistance in metabolically-driven cancers.磷酸甘油酸脱氢酶（PHGDH）作为代谢驱动型癌症耐药的一种机制。
Cancer Drug Resist. 2020;3(4):762-774. doi: 10.20517/cdr.2020.46. Epub 2020 Sep 17.
8
Prognostic significance of phosphoglycerate dehydrogenase in breast cancer.磷酸甘油酸脱氢酶在乳腺癌中的预后意义。
Breast Cancer Res Treat. 2021 Apr;186(3):655-665. doi: 10.1007/s10549-021-06123-9. Epub 2021 Feb 24.
9
Phosphoglycerate dehydrogenase promotes pancreatic cancer development by interacting with eIF4A1 and eIF4E.磷酸甘油酸脱氢酶通过与 eIF4A1 和 eIF4E 相互作用促进胰腺癌的发展。
J Exp Clin Cancer Res. 2019 Feb 11;38(1):66. doi: 10.1186/s13046-019-1053-y.
10
Functional genomics reveal that the serine synthesis pathway is essential in breast cancer.功能基因组学揭示丝氨酸合成途径在乳腺癌中是必不可少的。
Nature. 2011 Aug 18;476(7360):346-50. doi: 10.1038/nature10350.

引用本文的文献

1
SLC27A5 inhibits cancer stem cells by inducing alternative polyadenylation of METTL14 in hepatocellular carcinoma.SLC27A5通过诱导肝细胞癌中METTL14的可变聚腺苷酸化来抑制癌症干细胞。
Genes Dis. 2024 Dec 10;12(4):101488. doi: 10.1016/j.gendis.2024.101488. eCollection 2025 Jul.
2
The COMPASS complex maintains the metastatic capacity imparted by a subpopulation of cells in UPS.COMPASS复合物维持了UPS中一个细胞亚群赋予的转移能力。
iScience. 2024 Jun 5;27(7):110187. doi: 10.1016/j.isci.2024.110187. eCollection 2024 Jul 19.
3
Serine metabolism remodeling after platinum-based chemotherapy identifies vulnerabilities in a subgroup of resistant ovarian cancers.基于铂类化疗后的丝氨酸代谢重编程鉴定出耐药性卵巢癌亚群的脆弱性。
Nat Commun. 2022 Aug 5;13(1):4578. doi: 10.1038/s41467-022-32272-6.

Author Correction: PHGDH heterogeneity potentiates cancer cell dissemination and metastasis.

作者信息

Rossi Matteo, Altea-Manzano Patricia, Demicco Margherita, Doglioni Ginevra, Bornes Laura, Fukano Marina, Vandekeere Anke, Cuadros Alejandro M, Fernández-García Juan, Riera-Domingo Carla, Jauset Cristina, Planque Mélanie, Alkan H Furkan, Nittner David, Zuo Dongmei, Broadfield Lindsay A, Parik Sweta, Pane Antonino Alejandro, Rizzollo Francesca, Rinaldi Gianmarco, Zhang Tao, Teoh Shao Thing, Aurora Arin B, Karras Panagiotis, Vermeire Ines, Broekaert Dorien, Elsen Joke Van, Knott Maximilian M L, Orth Martin F, Demeyer Sofie, Eelen Guy, Dobrolecki Lacey E, Bassez Ayse, Brussel Thomas Van, Sotlar Karl, Lewis Michael T, Bartsch Harald, Wuhrer Manfred, Veelen Peter van, Carmeliet Peter, Cools Jan, Morrison Sean J, Marine Jean-Christophe, Lambrechts Diether, Mazzone Massimiliano, Hannon Gregory J, Lunt Sophia Y, Grünewald Thomas G P, Park Morag, Rheenen Jacco van, Fendt Sarah-Maria

机构信息

Laboratory of Cellular Metabolism and Metabolic Regulation, VIB-KU Leuven Center for Cancer Biology, VIB, Leuven, Belgium.

Laboratory of Cellular Metabolism and Metabolic Regulation, Department of Oncology, KU Leuven and Leuven Cancer Institute (LKI), Leuven, Belgium.

出版信息

Nature. 2022 Sep;609(7927):E8. doi: 10.1038/s41586-022-05226-7.

DOI:10.1038/s41586-022-05226-7
PMID:36042336
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9904429/
Abstract
摘要