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骨与关节疾病患者寻求物理治疗干预时维生素 D 缺乏的相关因素:一项基于医院的观察性研究。

Factors associated with vitamin D deficiency among patients with musculoskeletal disorders seeking physiotherapy intervention: a hospital-based observational study.

机构信息

Department of Physiotherapy and Rehabilitation, Uttara Adhunik Medical College and Hospital, Sector-09, Uttara Model Town, Dhaka, 1230, Bangladesh.

Low Back Research Team, College of Science, Health & Engineering, La Trobe University, Bundoora, VIC, Australia.

出版信息

BMC Musculoskelet Disord. 2022 Aug 30;23(1):817. doi: 10.1186/s12891-022-05774-z.

DOI:10.1186/s12891-022-05774-z
PMID:36042435
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9426039/
Abstract

BACKGROUND

A considerable number of studies have suggested that there is a strong correlation between 25-hydroxyvitamin D or vitamin D levels and overall health, with reported impacts ranging from mental health and vital organ health to musculoskeletal health. This study aimed to determine the prevalence of 25-hydroxyvitamin D deficiency and identify its associated factors among patients with musculoskeletal disorders (MSDs) currently seeking medical attention.

METHODS

A total of 143 patients with MSDs were randomly selected for blood sample collection to measure serum 25-hydroxyvitamin D levels. Descriptive statistics were used to describe the demographic and clinical characteristics of the study participants. Multiple logistic regression analyses were performed to compute the adjusted odds ratio.

RESULTS

Overall, 53.1% of patients had vitamin D deficiency. Vitamin D deficiency was more prevalent among patients with higher body mass index, a bachelor's degree, lower sun exposure time, and lower serum calcium levels and those living in an urban setting. The multiple logistic regression model suggested that the duration of weekly sun exposure and living location were the independent predictors of vitamin D deficiency.

CONCLUSION

It is recommended for patients with MSDs to participate in routine physical exercise, consume calcium- and vitamin D-enriched foods, and have regular sun exposure for minimizing the risk of vitamin D deficiency.

摘要

背景

大量研究表明,25-羟维生素 D 或维生素 D 水平与整体健康之间存在很强的相关性,其影响范围从心理健康和重要器官健康到肌肉骨骼健康。本研究旨在确定目前正在接受医疗的肌肉骨骼疾病(MSD)患者中 25-羟维生素 D 缺乏症的患病率,并确定其相关因素。

方法

随机选择了 143 名 MSD 患者采集血样,以测量血清 25-羟维生素 D 水平。采用描述性统计方法描述研究参与者的人口统计学和临床特征。采用多因素逻辑回归分析计算调整后的优势比。

结果

总体而言,53.1%的患者存在维生素 D 缺乏症。维生素 D 缺乏症在 BMI 较高、拥有学士学位、日照时间较短、血清钙水平较低以及居住在城市的患者中更为普遍。多因素逻辑回归模型提示,每周日照时间和居住地点是维生素 D 缺乏的独立预测因素。

结论

建议 MSD 患者定期进行常规体育锻炼、摄入富含钙和维生素 D 的食物并定期接受阳光照射,以降低维生素 D 缺乏症的风险。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77ec/9426039/ebfe3d9a299e/12891_2022_5774_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77ec/9426039/0749364a74eb/12891_2022_5774_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77ec/9426039/ebfe3d9a299e/12891_2022_5774_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77ec/9426039/0749364a74eb/12891_2022_5774_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/77ec/9426039/ebfe3d9a299e/12891_2022_5774_Fig2_HTML.jpg

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