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[通过模型模拟测试植入人工心脏的调节机制]

[Testing the regulation mechanism in inserting an artificial heart by model simulation].

作者信息

Hecht J, Körner E

出版信息

Z Exp Chir Transplant Kunstliche Organe. 1987;20(2):75-82.

PMID:3604358
Abstract

The problems of controlling the cardiac output and the balance of the blood volumes in the circulatory system were discussed for the natural heart as well as for an implanted artificial heart by means of a mathematical function model of the human organism. The control by the Starling mechanism (right atrial pressure) can adapt sufficiently the cardiac output according to the demands of the body, in case the loading steps do not exceed a fixed limit. The false regulation by a strong load of the organism is evidently caused by the limited capacity of the artificial heart and not by the strategy of the control.

摘要

通过人体的数学功能模型,讨论了天然心脏以及植入式人工心脏在控制心输出量和循环系统血容量平衡方面的问题。在负荷步骤不超过固定限度的情况下,通过斯塔林机制(右心房压力)进行的控制能够根据身体需求充分调节心输出量。机体受到强烈负荷时出现的错误调节显然是由人工心脏的有限容量导致的,而非控制策略所致。

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