双臂间收缩压差异：在非洲人群中的流行情况及相关因素。
Inter-arm difference in systolic blood pressure: Prevalence and associated factors in an African population.
机构信息
Faculty of Health Sciences, Laboratory of Chronic and Neurologic Diseases Epidemiology, LEMACEN, University of Abomey-Calavi, Cotonou, Benin.
INSERM, Univ. Limoges, CHU Limoges, IRD, U1094 Tropical Neuroepidemiology, Institute of Epidemiology and Tropical Neurology, GEIST, Limoges, France.
出版信息
PLoS One. 2022 Aug 31;17(8):e0272619. doi: 10.1371/journal.pone.0272619. eCollection 2022.
OBJECTIVES
Inter-arm blood pressure difference (IABPD) can lead to underdiagnosis and poor management of hypertension, when not recognized and are associated with increased cardiovascular mortality and morbidity. However, the prevalence and associated risk factors of IABPD in sub-Saharan Africa are unknown. This study aims to determine the prevalence and associated risk factors of IABPD among Tanve Health Study (TAHES) participants, a cohort about cardiovascular diseases in a rural area in Benin.
METHODS
The cohort was conducted since 2015 among adults aged 25 years and over in Tanve village. Data were collected from February to March, 2020. Brachial blood pressure were recorded at rest on both arm with an electronic device. Systolic IABPD (sIABPD) was defined as the absolute value of the difference in systolic blood pressure between left and right arms ≥ 10 mmHg. A multivariate logistic regression models identified factors associated with sIABPD.
RESULTS
A total of 1,505 participants (women 59%) were included. The mean age was 45.08 ±15.65 years. The prevalence of sIABPD ≥ 10 mmHg was 19% (95%CI: 17-21). It was 19% (95%CI: 16-22) in men and 20% (95%CI: 17-22) in women. In final multivariable model, the probability of sIABPD ≥ 10 mmHg increased significantly with age (adjusted OR (aOR) = 1.1; 95%CI: 1.02-1.20 per 10-years), hypertension (aOR = 2.33; 95%CI: 1.77-3.07) and diabetes (aOR = 1.96; 95%CI: 1.09-3.53).
CONCLUSION
Almost quarter of sample have a sIABPD ≥ 10 mmHg, with an increased risk with older age and hypertension and diabetes.
目的
手臂间血压差异（IABPD）如果未被识别，可能导致高血压诊断不足和治疗不佳，与心血管死亡率和发病率增加相关。然而，在撒哈拉以南非洲，IABPD 的患病率及其相关危险因素尚不清楚。本研究旨在确定贝宁农村 Tanve 健康研究（TAHES）参与者中 IABPD 的患病率及其相关危险因素。
方法
该队列研究于 2015 年开始，纳入年龄在 25 岁及以上的 Tanve 村成年人。数据于 2020 年 2 月至 3 月收集。使用电子设备在休息时记录双侧臂的血压。收缩期 IABPD（sIABPD）定义为左、右臂收缩压差值的绝对值≥10mmHg。采用多变量 logistic 回归模型确定与 sIABPD 相关的因素。
结果
共纳入 1505 名参与者（女性占 59%）。平均年龄为 45.08±15.65 岁。sIABPD≥10mmHg 的患病率为 19%（95%CI：17-21）。男性患病率为 19%（95%CI：16-22），女性患病率为 20%（95%CI：17-22）。在最终的多变量模型中，sIABPD≥10mmHg 的概率随年龄显著增加（调整后的比值比[aOR]为 1.1；95%CI：每增加 10 岁增加 1.02-1.20）、高血压（aOR=2.33；95%CI：1.77-3.07）和糖尿病（aOR=1.96；95%CI：1.09-3.53）。
结论
近四分之一的样本存在 sIABPD≥10mmHg，且随着年龄的增长、高血压和糖尿病，风险增加。
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