宾夕法尼亚州阿勒格尼县疫苗突破性病例中 SARS-CoV-2 的基因组特征。
Genomic characterization of SARS-CoV-2 from vaccine breakthrough cases in Allegheny County, Pennsylvania.
机构信息
Microbial Genomics Epidemiology Laboratory, Center for Genomic Epidemiology, University of Pittsburgh, Pittsburgh, Pennsylvania, United States of America.
Division of Infectious Diseases, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States of America.
出版信息
PLoS One. 2022 Aug 31;17(8):e0272954. doi: 10.1371/journal.pone.0272954. eCollection 2022.
We performed whole genome sequencing on SARS-CoV-2 from 59 vaccinated individuals from southwest Pennsylvania who tested positive between February and September, 2021. A comparison of mutations among vaccine breakthrough cases to a time-matched control group identified potential adaptive responses of SARS-CoV-2 to vaccination.
我们对 2021 年 2 月至 9 月期间在宾夕法尼亚州西南部检测呈阳性的 59 名接种过疫苗的个体的 SARS-CoV-2 进行了全基因组测序。疫苗突破病例中突变的比较与时间匹配的对照组鉴定出 SARS-CoV-2 对疫苗接种的潜在适应性反应。
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