Kren V, Mehta P, Rylko V, Flieger M, Kozová J, Sajdl P, Rehácek Z
Zentralbl Mikrobiol. 1987;142(1):71-85.
Regulation of the production of clavine alkaloids, especially elymoclavine, by sucrose, maltose, and mixtures of these saccharides was studied in submerged cultures of strains Claviceps purpurea 129/35 and Claviceps sp. SD-58. The data were statistically processed on an EC 1040 computer. Fermentation medium containing sucrose (80 g/l) in combination with glucose (20 g/l) was the best for elymoclavine formation. Retarded release of glucose from maltose increased the formation of elymoclavine and suppressed the synthesis of undesirable extracellular glucans. Carbon source can affect both the total amount of produced alkaloids and the relative proportion of individual clavines in the alkaloid mixture.
在紫麦角菌129/35菌株和麦角菌属SD - 58菌株的深层培养中，研究了蔗糖、麦芽糖以及这些糖类混合物对棒麦角生物碱（尤其是野麦角碱）产生的调控作用。数据在EC 1040计算机上进行统计处理。含有蔗糖（80 g/l）与葡萄糖（20 g/l）组合的发酵培养基最有利于野麦角碱的形成。麦芽糖中葡萄糖的缓慢释放增加了野麦角碱的形成，并抑制了不良细胞外葡聚糖的合成。碳源既可以影响生物碱的总产量，也可以影响生物碱混合物中各个棒麦角碱的相对比例。
