Department of Clinical Studies, Ontario Veterinary College, University of Guelph, 50 Stone Road East, Guelph, Ontario, N1G 2W1, Canada.
Department of Companion Animals, Atlantic Veterinary College, University of Prince Edward Island, 550 University Ave, Charlottetown, Prince Edward Island, C1A 4P3, Canada.
J Vet Cardiol. 2022 Oct;43:70-80. doi: 10.1016/j.jvc.2022.07.001. Epub 2022 Jul 21.
In dogs, single lead ventricular pacing, ventricular sensing, inhibition response, rate adaptive (VVIR) pacemakers are routinely used to treat third degree atrioventricular block. The objectives of this study were to investigate the heart rate distribution in dogs with VVIR pacemakers, and report changes when activity settings were adjusted.
Eighteen client-owned dogs with VVIR pacemakers for third degree atrioventricular block.
This observational study consisted of a review of medical records of dogs with VVIR pacemakers. For dogs with >50% of paced beats at the lower pacing rate, the activity daily living (ADL) and exertion responses were increased. Re-evaluations were performed after 6-12 months.
Heart rate distribution similar to healthy dogs was absent for all dogs. In nine dogs, the ADL and exertion responses were increased to the highest level. Of these, three dogs showed no improvement in heart rate distribution; for two dogs, one with an epicardial pacemaker, several activity settings were adjusted and pacing at higher heart rates was observed at re-evaluation. Four dogs died or were lost to follow-up. Clinical signs had resolved for all dogs after pacemaker implantation.
Default activity settings of VVIR pacemakers do not result in heart rate distribution equivalent to healthy dogs. Increasing the ADL and exertion response settings to the highest levels did not improve the pacemaker rate response. Further investigations into the role of dog size, generator positioning, pacemaker settings, and whether rate responsiveness is required for dogs' quality and quantity of life are warranted.
在犬中,单导联心室起搏、心室感知、抑制反应、速率适应性(VVIR)起搏器通常用于治疗三度房室传导阻滞。本研究的目的是研究 VVIR 起搏器犬的心率分布,并报告活动设置调整时的变化。
18 只患有三度房室传导阻滞的 VVIR 起搏器的患犬。
这是一项观察性研究,对 VVIR 起搏器犬的病历进行了回顾。对于起搏率低于 50%的起搏率高于 50%的犬,活动日常生活(ADL)和运动反应会增加。6-12 个月后进行重新评估。
所有犬的心率分布均与健康犬不同。在 9 只犬中,ADL 和运动反应增加到最高水平。其中 3 只犬的心率分布无改善;2 只犬(其中 1 只为心外膜起搏器),调整了几个活动设置,在重新评估时观察到更高心率的起搏。4 只犬死亡或失访。所有犬在起搏器植入后临床症状均得到缓解。
VVIR 起搏器的默认活动设置不能使心率分布与健康犬相当。将 ADL 和运动反应设置增加到最高水平并不能改善起搏器的反应速度。需要进一步研究犬的大小、发生器定位、起搏器设置以及是否需要心率反应性来提高犬的生活质量和数量。