早产儿低流量鼻导管吸氧需求：临床过程的预测因素及描述
Low flow nasal cannula requirement among preterm infants: predictors and description of clinical course.
作者信息
Daigneault Jaclyn, Horgan Megan, White Heather, Lee Austin, Rhein Lawrence
机构信息
Division of Neonatology, University of Massachusetts Medical School, Worcester, MA, USA.
Department of Population and Quantitative Health Sciences, University of Massachusetts Medical School, Worcester, MA, USA.
出版信息
J Perinatol. 2022 Dec;42(12):1680-1685. doi: 10.1038/s41372-022-01498-z. Epub 2022 Aug 31.
OBJECTIVE
We aim to identify potential risk factors associated with longer duration of supplemental oxygen use in preterm infants at risk for bronchopulmonary dysplasia (BPD) to better inform families and weaning protocols.
STUDY DESIGN
This is a retrospective study of infants with a birth gestational age (GA) < 32 0/7 weeks admitted to the neonatal intensive care unit (NICU) between October 2017 and September 2019.
RESULTS
A total of 172 infants met criteria for inclusion and analysis, of which 69 (40.1%) infants required LFNC. Risk factors for longer duration included lower birth GA or birth weight, increased ventilator days, and diagnosis of a patent ductus arteriosus (PDA). BPD was diagnosed in 69.6% who required LFNC, of which 47.8% were discharged on home oxygen.
CONCLUSION
Younger birth GA, lower birth weight, increased ventilator days, and presence of a PDA were identified as risk factors for longer LFNC duration.
目的
我们旨在确定与支气管肺发育不良（BPD）风险的早产儿使用补充氧气时间延长相关的潜在风险因素，以便更好地为家庭和撤机方案提供信息。
研究设计
这是一项对2017年10月至2019年9月间入住新生儿重症监护病房（NICU）、出生胎龄（GA）<32 0/7周的婴儿进行的回顾性研究。
结果
共有172名婴儿符合纳入和分析标准，其中69名（40.1%）婴儿需要低流量鼻导管吸氧（LFNC）。吸氧时间延长的风险因素包括较低的出生胎龄或出生体重、机械通气天数增加以及动脉导管未闭（PDA）的诊断。在需要LFNC的婴儿中，69.6%被诊断为BPD，其中47.8%出院时仍在家中吸氧。
结论
出生胎龄小、出生体重低、机械通气天数增加以及存在PDA被确定为LFNC持续时间延长的风险因素。
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