Department of Orthopaedic Surgery, Keio University School of Medicine, Tokyo, Japan.
Keio Spine Research Group (KSRG), Tokyo, Japan.
Spinal Cord. 2022 Oct;60(10):928-933. doi: 10.1038/s41393-022-00848-0. Epub 2022 Aug 31.
Retrospective multicenter study.
To compare the surgical outcomes and complications of posterior decompression between individuals with cervical spondylotic myelopathy (CSM) and those with ossification of the posterior longitudinal ligament (OPLL).
Seventeen medical institutions in Japan.
This study included 814 individuals with CSM (n = 636) and OPLL (n = 178) who underwent posterior decompression. Propensity score matching of the baseline characteristics was performed to compare surgical outcomes and perioperative complications between the CSM and OPLL groups.
Before propensity score matching, the OPLL group had higher percentage of male individuals, body mass index, and number of stenosis levels and longer duration of symptoms (P < 0.01, P < 0.01, P < 0.01, and P < 0.01, respectively). After matching, the baseline characteristics were comparable between the CSM (n = 98) and OPLL (n = 98) groups. The postoperative Japanese Orthopaedic Association (JOA) scores, preoperative-to-postoperative changes in the JOA scores, and JOA score recovery rates were not significantly different between the groups (P = 0.42, P = 0.47, and P = 0.09, respectively). The postoperative visual analog scale (VAS) score for neck pain and preoperative-to-postoperative changes in the VAS score for neck pain were not significantly different between the groups (P = 0.25 and P = 0.50, respectively). The incidence of perioperative complications was comparable between groups.
Neurological improvement and complication rates after surgery were comparable between individuals with CSM and those with OPLL, suggesting similar effectiveness and safety of posterior decompression for both conditions.
回顾性多中心研究。
比较伴有颈椎病(CSM)和后纵韧带骨化(OPLL)患者行后路减压术的手术结果和并发症。
日本的 17 家医疗机构。
本研究纳入了 814 例行后路减压术的 CSM 患者(n=636)和 OPLL 患者(n=178)。采用倾向评分匹配法对基线特征进行匹配,比较 CSM 组和 OPLL 组的手术结果和围手术期并发症。
在进行倾向评分匹配前,OPLL 组男性比例、体质指数、狭窄节段数和症状持续时间均较高(P<0.01、P<0.01、P<0.01 和 P<0.01)。匹配后,CSM 组(n=98)和 OPLL 组(n=98)的基线特征具有可比性。两组术后日本骨科协会(JOA)评分、术前至术后 JOA 评分变化以及 JOA 评分恢复率无显著差异(P=0.42、P=0.47 和 P=0.09)。两组术后颈痛视觉模拟量表(VAS)评分和术前至术后颈痛 VAS 评分变化无显著差异(P=0.25 和 P=0.50)。两组围手术期并发症发生率无显著差异。
CSM 患者和 OPLL 患者术后神经功能改善和并发症发生率相当,提示后路减压术对这两种疾病具有相似的有效性和安全性。