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后路纵韧带骨化症和椎间盘突出症所致脊髓型颈椎病的混合椎体次全切除术及椎间盘置换术

Hybrid Corpectomy and Disc Arthroplasty for Cervical Spondylotic Myelopathy Caused by Ossification of Posterior Longitudinal Ligament and Disc Herniation.

作者信息

Chang Huang-Chou, Tu Tsung-Hsi, Chang Hsuan-Kan, Wu Jau-Ching, Fay Li-Yu, Chang Peng-Yuan, Wu Ching-Lan, Huang Wen-Cheng, Cheng Henrich

机构信息

Department of Surgery, Kaohsiung Veterans General Hospital, Kaohsiung, Taiwan.

Department of Neurosurgery, Neurological Institute, Taipei Veterans General Hospital, Taipei, Taiwan; School of Medicine, National Yang-Ming University, Taipei, Taiwan.

出版信息

World Neurosurg. 2016 Nov;95:22-30. doi: 10.1016/j.wneu.2016.07.065. Epub 2016 Jul 26.

Abstract

OBJECTIVE

The combination of anterior cervical discectomy and fusion (ACDF) and anterior cervical corpectomy and fusion (ACCF) has been demonstrated to be effective for multilevel cervical spondylotic myelopathy (CSM); however, the combination of ACCF and cervical disc arthroplasty (CDA) for 3-level CSM has never been addressed.

METHODS

Consecutive patients (>18 years of age) with CSM caused by segmental ossification of posterior longitudinal ligament (OPLL) and degenerative disc disease (DDD) were reviewed. Inclusion criteria were patients who underwent hybrid ACCF and CDA surgery for symptomatic 3-level CSM with OPLL and DDD. Medical and radiologic records were reviewed retrospectively.

RESULTS

A total of 15 patients were analyzed with a mean follow-up of 18.1 ± 7.42 months. Every patient had hybrid surgery composed of 1-level ACCF (for segmental-type OPLL causing spinal stenosis) and 1-level CDA at the adjacent level (for DDD causing stenosis). All clinical outcomes, including visual analogue scale of neck and arm pain, Neck Disability Index, Japanese Orthopedic Association scores, and Nurick scores of myelopathy, demonstrated significant improvement at 12 months after surgery. All patients (100%) achieved arthrodesis for the ACCF (instrumented) and preserved mobility for CDA (preoperation 6.2 ± 3.81° vs. postoperation 7.0 ± 4.18°; P = 0.579).

CONCLUSIONS

For patients with multilevel CSM caused by segmental OPLL and DDD, the hybrid surgery of ACCF and CDA demonstrated satisfactory clinical and radiologic outcomes. Moreover, although located next to each other, the instrumented ACCF construct and CDA still achieved solid arthrodesis and preserved mobility, respectively. Therefore, hybrid surgery may be a reasonable option for the management of CSM with OPLL.

摘要

目的

颈前路椎间盘切除融合术(ACDF)与颈前路椎体次全切除融合术(ACCF)联合应用已被证明对多节段脊髓型颈椎病(CSM)有效;然而,ACCF与颈椎间盘置换术(CDA)联合治疗3节段CSM的情况尚未见报道。

方法

回顾性分析连续收治的因后纵韧带骨化症(OPLL)和椎间盘退变疾病(DDD)导致CSM的患者(年龄>18岁)。纳入标准为因有症状的3节段CSM伴OPLL和DDD接受ACCF与CDA联合手术的患者。对患者的医学和影像学记录进行回顾性分析。

结果

共分析15例患者,平均随访18.1±7.42个月。每位患者均接受了由1节段ACCF(用于节段型OPLL导致的椎管狭窄)和相邻节段1节段CDA(用于DDD导致的狭窄)组成的联合手术。所有临床指标,包括颈部和手臂疼痛视觉模拟量表、颈部功能障碍指数、日本矫形外科学会评分以及脊髓病的Nurick评分,在术后12个月均显示出显著改善。所有患者(100%)的ACCF(内固定)均实现了融合,CDA保持了活动度(术前6.2±3.81° vs.术后7.0±4.18°;P = 0.579)。

结论

对于因节段型OPLL和DDD导致的多节段CSM患者,ACCF与CDA联合手术显示出令人满意的临床和影像学效果。此外,尽管ACCF内固定结构和CDA相邻,但仍分别实现了牢固融合和保留了活动度。因此,联合手术可能是治疗伴有OPLL的CSM的合理选择。

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