Noor Research Center for Ophthalmic Epidemiology, Noor Eye Hospital, Tehran, Iran.
Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran.
BMC Ophthalmol. 2022 Aug 31;22(1):354. doi: 10.1186/s12886-022-02578-6.
To determine the age and sex-standardized prevalence of corneal arcus and its associated factors in a geriatric population.
This population-based cross-sectional study was conducted in 2019 in Tehran; the capital of Iran, using a multi-stage stratified random cluster sampling method. All participants underwent a detailed interview, blood pressure measurement, laboratory blood tests, and a complete ocular examination.
Three thousand three hundred ten of 3791 invitees participated in the study (response rate: 87.31%). The mean age of the participants was 69.35 ± 7.62 years (60-97 years) and 1912 (57.76%) were female. Overall, the age and sex-standardized prevalence (95% CI) of corneal arcus was 44.28% (41.21-47.39). Based on the multiple logistic regression, the odds of corneal arcus were higher in men than in women (OR: 1.51; 95% CI: 1.14-2.00); in the age group ≥ 80 years compared to the age group 60-64 years (OR: 2.44; 95% CI: 1.68-3.53), and in retired people compared to employed individuals (OR: 2.05; 95% CI: 1.31-3.21).
The present study showed a high prevalence of corneal arcus in the geriatric population. Although various studies have reported a significant relationship between corneal arcus with blood lipid and glucose levels as well as blood pressure, these relationships were not found in the present study.
确定老年人群中角膜弓的年龄和性别标准化患病率及其相关因素。
本研究为 2019 年在伊朗首都德黑兰进行的一项基于人群的横断面研究,采用多阶段分层随机聚类抽样方法。所有参与者均接受详细访谈、血压测量、实验室血液检查和全面眼部检查。
在 3791 名受邀者中,有 3310 名(回应率:87.31%)参加了研究。参与者的平均年龄为 69.35±7.62 岁(60-97 岁),其中 1912 名(57.76%)为女性。总体而言,角膜弓的年龄和性别标准化患病率(95%CI)为 44.28%(41.21-47.39)。基于多元逻辑回归分析,男性发生角膜弓的几率高于女性(OR:1.51;95%CI:1.14-2.00);年龄组≥80 岁的参与者比 60-64 岁年龄组的参与者(OR:2.44;95%CI:1.68-3.53)以及退休人员比在职人员(OR:2.05;95%CI:1.31-3.21)更高。
本研究显示老年人群中角膜弓的患病率较高。尽管多项研究报道角膜弓与血脂、血糖水平以及血压之间存在显著关系,但本研究未发现这些关系。