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高脂血症并不影响髋关节撞击综合征关节镜治疗的临床结果。

Hyperlipidemia does not influence clinical outcome in arthroscopic treatment of femoroacetabular impingement syndrome.

机构信息

Department of Sports Medicine, Beijing Key Laboratory of Sports Injuries, Institute of Sports Medicine of Peking University, Peking University Third Hospital, 49 North Garden Rd., Haidian District, Beijing, 100191, People's Republic of China.

出版信息

J Orthop Surg Res. 2022 Aug 31;17(1):398. doi: 10.1186/s13018-022-03290-3.

DOI:10.1186/s13018-022-03290-3
PMID:36045389
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9429662/
Abstract

BACKGROUND

Cholesterol can trigger degenerative processes in the chondrocytes. The internal layer of the hip labral consists of cartilage-specific type II collagen-positive fibrocartilage. The purpose of this study was to compare outcomes after arthroscopy labral repair in FAIS patients with preoperative hyperlipidemia to a control group with no hyperlipidemia.

METHODS

Data were prospectively collected and retrospectively reviewed for FAIS patients who had arthroscopy 2019. Patients with hyperlipidemia were 1:1 propensity-score matched to patients without hyperlipidemia. Patient-reported outcomes (HOS-ADL, iHOT-12, mHHS), VAS scores, radiographic measures, performed procedures, complications, and revision surgery were compared and analyzed for both groups.

RESULTS

A total of 41 patients with hyperlipidemia and 41 patients without hyperlipidemia were found using propensity-score matching. When compared to preoperative levels, both groups demonstrated significant improvements in PROs and VAS scores at the final follow-up. Besides, there were no significant differences in preoperative scores and final outcome scores between the groups. Besides, there were no other differences in revision rate and the rate of meeting the PASS and MCID between the study and the control groups.

CONCLUSION

It was demonstrated in this study that FAIS patients with hyperlipidemia can expect to experience similar good short-term patient-reported outcomes as compared with patients without hyperlipidemia.

LEVEL OF EVIDENCE

Case-series study; Level of Evidence: Level III.

摘要

背景

胆固醇可引发软骨细胞的退行性变化。髋关节唇的内层由软骨特异性 II 型胶原阳性纤维软骨组成。本研究旨在比较术前高脂血症的 FAIS 患者与无高脂血症的对照组行关节镜下唇修复术后的结果。

方法

前瞻性收集数据并回顾性分析 2019 年行关节镜检查的 FAIS 患者。将高脂血症患者与无高脂血症患者进行 1:1 倾向评分匹配。比较两组患者的报告结果(HOS-ADL、iHOT-12、mHHS)、VAS 评分、影像学测量值、手术操作、并发症和翻修手术,并进行分析。

结果

通过倾向评分匹配共找到 41 例高脂血症患者和 41 例无高脂血症患者。与术前水平相比,两组患者在最终随访时的 PRO 和 VAS 评分均显著改善。此外,两组患者的术前评分和最终结局评分之间无显著差异。此外,两组在翻修率和 PASS、MCID 方面的差异无统计学意义。

结论

本研究表明,高脂血症的 FAIS 患者可以预期与无高脂血症的患者一样获得良好的短期患者报告结果。

证据水平

病例系列研究;证据等级:III 级。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a42/9429662/e3b59c25bd57/13018_2022_3290_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a42/9429662/e3b59c25bd57/13018_2022_3290_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5a42/9429662/e3b59c25bd57/13018_2022_3290_Fig1_HTML.jpg

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