Suppr超能文献

欧陆明(巴瑞替尼)口服片剂:深入了解美国食品药品监督管理局批准的斑秃系统性治疗药物

Olumniant (Baricitinib) oral tablets: An insight into FDA-approved systemic treatment for Alopecia Areata.

作者信息

Ali Eman, Owais Rabia, Sheikh Ayesha, Shaikh Asim

机构信息

Department of Internal Medicine, Dow University of Health Sciences, Karachi, Pakistan.

出版信息

Ann Med Surg (Lond). 2022 Jul 13;80:104157. doi: 10.1016/j.amsu.2022.104157. eCollection 2022 Aug.

Abstract

Olumniant (Barcitinib) has gained swift approval by the Food and Drug Administration (FDA) as a promising medication for the treatment of adults with severe Alopecia Areata. This drug has proven to be effective for various conditions including Covid-19 and Rheumatoid Arthritis as well as being found to be less costly and minimally invasive, with no need for post-operative management. However, its use has some considerable potential implications before its prescription can be made commonplace. Therefore, more trials need to be conducted to establish a more rigid safety profile.

摘要

欧鲁明(巴瑞替尼)已迅速获得美国食品药品监督管理局(FDA)的批准,成为一种有前景的药物,用于治疗重度斑秃的成年人。这种药物已被证明对包括新冠病毒病和类风湿性关节炎在内的各种病症有效,而且成本较低、侵入性极小,无需术后管理。然而,在其处方变得普遍之前,其使用存在一些相当大的潜在影响。因此,需要进行更多试验以建立更严格的安全档案。

相似文献

3
Therapeutic Response of Alopecia Areata-Associated Nail Changes to Baricitinib.斑秃相关甲改变对巴瑞替尼的治疗反应
Case Rep Dermatol Med. 2024 Aug 31;2024:8879884. doi: 10.1155/2024/8879884. eCollection 2024.
8
Off-Label Use of Baricitinib in Dermatology.巴瑞替尼在皮肤科的超适应证使用。
J Drugs Dermatol. 2023 Aug 1;22(8):795-801. doi: 10.36849/jdd.7360.
9
Emerging drugs for alopecia areata: JAK inhibitors.斑秃的新兴药物:JAK 抑制剂。
Expert Opin Emerg Drugs. 2018 Mar;23(1):77-81. doi: 10.1080/14728214.2018.1444750. Epub 2018 Feb 26.
10
Application of Baricitinib in Dermatology.巴瑞替尼在皮肤科的应用。
J Inflamm Res. 2022 Mar 18;15:1935-1941. doi: 10.2147/JIR.S356316. eCollection 2022.

引用本文的文献

5
Pharmaceutical aspects of JAK inhibitors: a comparative review.JAK抑制剂的药学方面:比较性综述。
Inflammopharmacology. 2025 Jan;33(1):91-104. doi: 10.1007/s10787-024-01614-9. Epub 2024 Dec 11.

本文引用的文献

1
A Comprehensive Literature Review of JAK Inhibitors in Treatment of Alopecia Areata.JAK抑制剂治疗斑秃的综合文献综述
Clin Cosmet Investig Dermatol. 2021 Jun 25;14:691-714. doi: 10.2147/CCID.S309215. eCollection 2021.
4
Baricitinib: From Rheumatoid Arthritis to COVID-19.巴瑞替尼:从类风湿关节炎到 COVID-19。
J Clin Pharmacol. 2021 Oct;61(10):1274-1285. doi: 10.1002/jcph.1874. Epub 2021 Jun 12.
10
Alopecia Areata. Current situation and perspectives.斑秃。现状与展望。
Arch Argent Pediatr. 2017 Dec 1;115(6):e404-e411. doi: 10.5546/aap.2017.eng.e404.

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验