Wondwosen Mekete, Bacha Ayantu, Nibret Yonas, Tantu Temesgen, Zewdu Dereje
Department of Surgery, College of Medicine and Health Science, Wolkite University, Wolkite, Ethiopia.
Department of Dermatology and Venereology, College of Medicine and Health Science, Addis Ababa University, Addis Ababa, Ethiopia.
Ann Med Surg (Lond). 2022 Aug 1;80:104298. doi: 10.1016/j.amsu.2022.104298. eCollection 2022 Aug.
Fibroadenoma of the male breast is a rarely diagnosed lesion that often occurs concurrently with gynecomastia and the intake of medications that alter sex hormone levels. Herein, we report the first case of fibroadenoma of the male breast, presenting with medullary thyroid cancer. In addition, we reviewed the current management strategies for fibroadenoma of the male breast in the literature.
A 25-year-old male patient presented to our surgical unit with medullary thyroid cancer (MTC). The physical examination revealed an unnoticed lump in his left breast. We delayed the planned thyroid surgery to determine whether the breast mass was associated with metastasis from MTC. We performed pathological tests from excised breast mass and confirmed the diagnosis of fibroadenoma. After confirming the benign nature of the breast mass, the patient underwent total thyroidectomy with selective neck dissection for MTC.
Fibroadenoma of the male breast was diagnosed based on clinical presentation and histopathological findings. Fibroadenoma of the male breast is a rarely diagnosed lesion: and is often associated with gynecomastia and altered serum sex hormone level. The presentation of this case without those concurrences is even rarer, as revealed in our case. The management for suspected fibroadenoma of the male breast presented with MTC should include delaying the thyroid surgery to rule out the presence of malignancy and metastasis.
The finding indicates that fibroadenoma can be considered a differential diagnosis in the male breast even in the absence of those concurrences. The timely diagnosis and orderly management of fibroadenoma of the male breast and MTC could help to improve the patient outcome.
男性乳腺纤维腺瘤是一种罕见的诊断病变，常与男性乳房发育及服用改变性激素水平的药物同时发生。在此，我们报告首例男性乳腺纤维腺瘤合并甲状腺髓样癌的病例。此外，我们回顾了文献中目前关于男性乳腺纤维腺瘤的治疗策略。
一名25岁男性患者因甲状腺髓样癌（MTC）就诊于我们的外科病房。体格检查发现其左乳有一个之前未被注意到的肿块。我们推迟了计划中的甲状腺手术，以确定乳腺肿块是否与MTC转移有关。我们对切除的乳腺肿块进行了病理检查，确诊为纤维腺瘤。在确认乳腺肿块为良性后，患者接受了甲状腺全切术及针对MTC的选择性颈部淋巴结清扫术。
男性乳腺纤维腺瘤根据临床表现和组织病理学发现进行诊断。男性乳腺纤维腺瘤是一种罕见的诊断病变，常与男性乳房发育及血清性激素水平改变有关。如我们的病例所示，该病例无这些并发情况的表现更为罕见。对于疑似合并MTC的男性乳腺纤维腺瘤的处理应包括推迟甲状腺手术以排除恶性肿瘤及转移的存在。
该发现表明，即使没有这些并发情况，纤维腺瘤也可被视为男性乳腺的鉴别诊断之一。对男性乳腺纤维腺瘤和MTC的及时诊断及有序处理有助于改善患者的预后。
