Anandan Aathavan Shanmuga, Silva Munasinghe
Faculty of Medicine, The University of Queensland, St. Lucia, Queensland, Australia.
Ann Med Surg (Lond). 2022 Jul 20;80:104138. doi: 10.1016/j.amsu.2022.104138. eCollection 2022 Aug.
With rising rates of atherosclerotic disease and obesity worldwide, the prevalence of chronic mesenteric ischemia (CMI) has been progressively rising. Prompt diagnosis and early intervention are crucial to avoid bowel loss and mortality in optimising long-term outcomes for patients and achieving symptom relief.
This article aims to summarise relevant literature on CMI, enabling primary care physicians to make a timely diagnosis and intervention, improving outcomes of patients with CMI.
CMI is often mistaken for more common pathologies due to its non-specific history and physical examination findings. A missed diagnosis can end up in acute mesenteric infarction and bowel perforation which can cause severe morbidity and mortality. Thus, a thorough gastrointestinal disease work-up ruling out other conditions may be required. CT angiogram is the gold standard non-invasive investigation for confirming a CMI diagnosis. Referral to vascular surgery with early surgical intervention through angioplasty and stenting is crucial for improving patient outcomes. Long-term follow-up of patients through routine consultations and serial non-invasive imaging can monitor for recurrence and disease progression.
随着全球动脉粥样硬化疾病和肥胖率的上升,慢性肠系膜缺血(CMI)的患病率也在逐渐上升。及时诊断和早期干预对于避免肠坏死和死亡至关重要,这有助于优化患者的长期预后并缓解症状。
本文旨在总结关于CMI的相关文献,使基层医疗医生能够及时进行诊断和干预,改善CMI患者的预后。
由于CMI的病史和体格检查结果不具特异性,它常被误诊为更常见的病症。漏诊可能导致急性肠系膜梗死和肠穿孔,进而引发严重的发病率和死亡率。因此,可能需要进行全面的胃肠道疾病检查以排除其他病症。CT血管造影是确诊CMI的金标准无创检查。早期通过血管成形术和支架置入进行手术干预并转诊至血管外科,对于改善患者预后至关重要。通过定期会诊和系列无创成像对患者进行长期随访,可以监测复发情况和疾病进展。