Goldman-Yassen Adam E, Derman Anna, Madan Rebecca Pellett, Radmanesh Alireza
Department of Radiology, Children's Healthcare of Atlanta, 1405 Clifton Rd. NE Atlanta, GA 30322, USA.
Department of Radiology and Imaging Sciences, Emory University School of Medicine, 201 Dowman Dr, Atlanta, GA 30322, USA.
Case Rep Radiol. 2022 Aug 21;2022:5199863. doi: 10.1155/2022/5199863. eCollection 2022.
The raccoon roundworm () may infect humans to cause severe or fatal meningoencephalitis, as well as ocular and visceral larva migrans. Young children are at greater risk for cerebral larva migrans with severe meningoencephalitis, and early empiric therapy may improve outcomes. Familiarity with characteristic brain imaging findings may prompt earlier diagnosis, particularly in the setting of CSF eosinophilia. We report a case of a 19-month-old boy who presented with truncal ataxia and was found to have peripheral and CSF eosinophilia. MRI demonstrated symmetric, confluent T2 hyperintense signal in the cerebral and cerebellar deep white mater, which helped differentiate meningoencephalitis from other infectious and non-infectious causes of eosinophilic meningoencephalitis. Early recognition and treatment of meningoencephalitis are important for improved outcomes, and careful review of neuroimaging can play a critical role in suggesting the diagnosis.
浣熊蛔虫()可感染人类,导致严重或致命的脑膜脑炎,以及眼部和内脏幼虫移行症。幼儿患脑幼虫移行症并伴有严重脑膜脑炎的风险更高,早期经验性治疗可能改善预后。熟悉特征性的脑成像表现可能促使早期诊断,尤其是在脑脊液嗜酸性粒细胞增多的情况下。我们报告一例19个月大男孩,表现为躯干共济失调,外周血和脑脊液嗜酸性粒细胞增多。磁共振成像显示大脑和小脑深部白质对称、融合的T2高信号,这有助于将脑膜脑炎与嗜酸性粒细胞性脑膜脑炎的其他感染性和非感染性病因相鉴别。早期识别和治疗浣熊蛔虫脑膜脑炎对改善预后很重要,仔细审查神经影像学在提示诊断方面可发挥关键作用。