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一名患有非致命性脑膜脑炎婴儿的浣熊贝利斯蛔虫感染的诊断与处理

Diagnosis and management of Baylisascaris procyonis infection in an infant with nonfatal meningoencephalitis.

作者信息

Cunningham C K, Kazacos K R, McMillan J A, Lucas J A, McAuley J B, Wozniak E J, Weiner L B

机构信息

Department of Pediatrics, SUNY Health Science Center at Syracuse 13210.

出版信息

Clin Infect Dis. 1994 Jun;18(6):868-72. doi: 10.1093/clinids/18.6.868.

Abstract

Baylisacaris procyonis, the common raccoon ascarid, is known to cause life-threatening visceral, neural, and ocular larva migrans in mammals and birds. Two human fatalities have been previously described; however, little is known about the spectrum of human disease caused by B. procyonis. In this report, the case of a 13-month-old child who had nonfatal meningoencephalitis secondary to B. procyonis infection is presented. The suspected diagnosis was confirmed with use of newly developed enzyme immunoassay and immunoblot techniques. The diagnosis, management, and prevention of B. procyonis infection in humans is discussed. Clinical, serological, and epidemiological evaluations established B. procyonis as the etiologic agent. The child survived his infection but continued to have severe neurological sequelae. The potential for human contact and infection with B. procyonis is great. There is no effective therapy; therefore, prevention is paramount.

摘要

浣熊贝利斯蛔虫,即常见的浣熊蛔虫,已知可在哺乳动物和鸟类中引发危及生命的内脏、神经和眼部幼虫移行症。此前已有两例人类死亡病例的报道;然而,对于由浣熊贝利斯蛔虫引起的人类疾病谱,人们了解甚少。在本报告中,介绍了一名13个月大的儿童因感染浣熊贝利斯蛔虫继发非致命性脑膜脑炎的病例。通过使用新开发的酶免疫测定和免疫印迹技术,确诊了疑似诊断。文中讨论了人类感染浣熊贝利斯蛔虫的诊断、管理和预防。临床、血清学和流行病学评估确定浣熊贝利斯蛔虫为病原体。该儿童感染后存活下来,但仍有严重的神经后遗症。人类接触和感染浣熊贝利斯蛔虫的可能性很大。目前尚无有效治疗方法;因此,预防至关重要。

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