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一名患有系统性红斑狼疮且近期感染冠状病毒的患者发生自发性气胸。

Spontaneous Pneumothorax in a Patient with Systemic Lupus Erythematosus and Recent Infection with Coronavirus.

作者信息

Graves Nicholas, Flint Julia, Sagdeo Amol, Askari Ayman, Ball Patrick, Morrissey Hana

机构信息

School of Medicine, David Weatherall Building, University Road, Keele University, Staffordshire ST5 5BG, UK.

The Robert Jones and Agnes Hunt Orthopaedic Hospital, NHS Foundation Trust, SY10 7AG, UK.

出版信息

Case Rep Pulmonol. 2022 Aug 22;2022:9594063. doi: 10.1155/2022/9594063. eCollection 2022.

DOI:10.1155/2022/9594063
PMID:36046751
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9424047/
Abstract

A 50-year-old woman with a history of systemic lupus erythematosus and a recent infection with COVID-19 presented to the emergency department with acute shortness of breath twice in 10 days. She was diagnosed with myopericarditis attributed to COVID-19 infection (first admission), and chest X-ray revealed a small left-sided pneumothorax, pericardial effusion (second admission), with no mediastinal shift or other signs of tension. Computed tomography confirmed these results and revealed a few small cysts in the right lung. An echocardiogram demonstrated normal heart anatomy and filling dynamics. The patient was diagnosed with simple pneumothorax and ongoing myopericarditis managed with colchicine, ibuprofen, and low-dose prednisolone. The patient responded to treatment and was discharged. Pneumothorax association with COVID-19 is reported in a small number of publications, but the association is less clear with SLE. Our patient may have been predisposed to developing pneumothorax after COVID-19 infection due to her existing connective tissue disorder.

摘要

一名50岁女性,有系统性红斑狼疮病史,近期感染了新冠病毒,10天内两次因急性气短到急诊科就诊。她被诊断为新冠病毒感染所致的心肌心包炎(首次入院),胸部X线显示左侧少量气胸、心包积液(第二次入院),无纵隔移位或其他张力性体征。计算机断层扫描证实了这些结果,并显示右肺有几个小囊肿。超声心动图显示心脏解剖结构和充盈动态正常。该患者被诊断为单纯性气胸和持续性心肌心包炎,采用秋水仙碱、布洛芬和小剂量泼尼松龙治疗。患者对治疗有反应并出院。少数出版物报道了气胸与新冠病毒的关联,但与系统性红斑狼疮的关联尚不清楚。我们的患者可能由于现有的结缔组织疾病,在感染新冠病毒后易发生气胸。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7e3/9424047/d64a60650d37/CRIPU2022-9594063.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7e3/9424047/39c5a2d683ab/CRIPU2022-9594063.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7e3/9424047/d64a60650d37/CRIPU2022-9594063.002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7e3/9424047/39c5a2d683ab/CRIPU2022-9594063.001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d7e3/9424047/d64a60650d37/CRIPU2022-9594063.002.jpg

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本文引用的文献

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Colchicine prevents disease progression in viral myocarditis via modulating the NLRP3 inflammasome in the cardiosplenic axis.秋水仙碱通过调节心脏-脾脏轴中的 NLRP3 炎性小体来预防病毒性心肌炎的疾病进展。
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