Laghari Fahad J, Eakin Sarah, El-Zuway Salem
Divisions of Neurology.
Pathology, and.
J Neurosurg Case Lessons. 2021 Feb 15;1(7):CASE20141. doi: 10.3171/CASE20141.
Previously, solitary and unilateral aggregates of intracranial subdural osteomas have been described. These tumors are thought to be slow growing and at times inconsequential on the basis of characteristics of subjacent brain. Unilateral location and history of traumas have led to the thought that the head trauma may play a role in pathogenesis.
The authors describe a unique case of a patient who was found to have bilateral intracranial subdural osteomas of unequal size on the basis of computed tomography and magnetic resonance imaging. The presenting symptom was headache. Initially small and thought to be irrelevant, these tumors grew over the course of 7 years to cause mass effect and effacement of the sulci and gyri. The larger 15-cm-long tumor was excised and was sent for pathology, which showed classic histology for subdural osteoma.
The described case uniquely demonstrates evidence of the slow growth of intracranial subdural osteomas over the course of years. It is crucial not to disregard the tumor because it can grow over time to cause mass effect. Patient follow-up is strongly recommended. Bilateral tumor occurrence at a similar location in this case supports an etiology other than trauma. Further research is necessary.
此前,已有关于颅内硬膜下骨瘤孤立性和单侧性聚集的描述。基于其下方脑组织的特征,这些肿瘤被认为生长缓慢,有时并不重要。单侧位置和外伤史引发了这样的想法,即头部外伤可能在其发病机制中起作用。
作者描述了一例独特病例,该患者经计算机断层扫描和磁共振成像发现双侧颅内硬膜下骨瘤大小不等。主要症状为头痛。这些肿瘤最初较小,被认为无关紧要,但在7年的时间里逐渐生长,导致占位效应,脑沟和脑回消失。切除了较大的15厘米长的肿瘤并送去做病理检查,结果显示为硬膜下骨瘤的典型组织学表现。
所描述的病例独特地证明了颅内硬膜下骨瘤在数年时间里缓慢生长的证据。至关重要的是,不要忽视这种肿瘤,因为它可能随时间推移而生长并导致占位效应。强烈建议对患者进行随访。该病例中双侧肿瘤出现在相似位置,这支持了除外伤以外的其他病因。有必要进行进一步研究。