Mattingly Thomas K, Lopez-Ojeda Pablo, Arango Miguel, Harle Chris, Kakani Nirmal, Allen Peter, Lehrbass Barbara, Lownie Stephen P
Departments of Neurosurgery.
Department of Neurosurgery, University of Rochester, Rochester, New York.
J Neurosurg Case Lessons. 2021 Feb 15;1(7):CASE2090. doi: 10.3171/CASE2090.
The authors present a case of selective hypothermia used for neuroprotection during clipping of a giant partially thrombosed middle cerebral artery (MCA) aneurysm. Although these cases have traditionally required deep hypothermic cardiac arrest, this case illustrates a novel and entirely endovascular solution that avoids cardiac standstill and whole-body cooling.
This is, to the authors' knowledge, the first case in human surgery of a catheter-based selective hypothermic circuit used to facilitate MCA trapping for almost 30 minutes. Core temperatures never dropped below 34°C, and the patient recovered uneventfully and has been well for over 5 years.
The technical nuances and physiological changes unique to selective hypothermia are discussed.
作者介绍了一例在夹闭巨大的部分血栓形成的大脑中动脉(MCA)动脉瘤时使用选择性低温进行神经保护的病例。尽管传统上这些病例需要深度低温心脏停搏,但该病例展示了一种新颖的完全血管内解决方案,可避免心脏停搏和全身降温。
据作者所知,这是人类手术中首例使用基于导管的选择性低温回路促进MCA阻断近30分钟的病例。核心温度从未降至34°C以下患者顺利康复,并且5年来一直状况良好。
讨论了选择性低温特有的技术细微差别和生理变化。