von Frenckell R
Acta Psychiatr Belg. 1987 Jan-Feb;87(1):85-91.
This short novel is the story of the perplexity of a statistician travelling for more than a decade in the quicksands of quantitative psychopathology, from the nonvalidated concepts of the DSM-III to their validation by the Dexamethasone Suppression Test whose validity is ignored, from the "mathematical" concepts of Lacan to items suppressed from the AMDP-System, such as autism, because of a lack of agreement of the psychiatrists on objective criteria. The author concludes with a note of hope: comprehensive scales like the AMDP, combined with biological predictors, should facilitate the discovery of new psychotropic drugs, more specific for certain syndromes, hence contributing to new classificatory models.
这部短篇小说讲述了一位统计学家在定量精神病理学的流沙中徘徊十多年的困惑历程，从《精神疾病诊断与统计手册》第三版未经证实的概念，到地塞米松抑制试验对其进行的验证，而该试验的有效性却被忽视；从拉康的“数学”概念，到由于精神科医生在客观标准上缺乏共识而从AMDP系统中删除的项目，比如自闭症。作者带着一丝希望总结道：像AMDP这样的综合量表，结合生物学预测指标，应该有助于发现对某些综合征更具特异性的新型精神药物，从而推动新的分类模型的发展。
