Zhou Xiaoxue, Zhang Ye, He Yihua
Echocardiography Medical Center, Beijing Anzhen Hospital, Capital Medical University, Beijing, China.
Maternal-Fetal Medicine Center in Fetal Heart Disease, Beijing Anzhen Hospital, Beijing, China.
Fetal Pediatr Pathol. 2023 Apr;42(2):327-333. doi: 10.1080/15513815.2022.2116619. Epub 2022 Sep 1.
Fetal unguarded tricuspid valve orifice (UTVO) is characterized by a complete or partial absence of the tricuspid valvular tissue or sub-valvular apparatus and only case reports are available at present. We report a UTVO diagnosed by fetal autopsy. An 18-week fetus was diagnosed by prenatal ultrasound with tricuspid dysplasia with 'to-and-fro' flow across the right-sided heart. Fetal autopsy showed partial agenesis of tricuspid valve instead of valvular dysplasia. This supported a diagnosis of UTVO. Fetal autopsy can differentiate UTVO form other valve abnormalities. The 'to-and-fro' flow pattern across the right atrioventricular orifice could be used to differentiate UTVO from other valve dysplasias on echocardiography.
胎儿无保护三尖瓣口（UTVO）的特征是三尖瓣组织或瓣下结构完全或部分缺失，目前仅有病例报告。我们报告一例经胎儿尸检确诊的UTVO。一名18周的胎儿经产前超声诊断为三尖瓣发育异常，右侧心脏有“往返”血流。胎儿尸检显示为三尖瓣部分发育不全而非瓣膜发育异常。这支持了UTVO的诊断。胎儿尸检可将UTVO与其他瓣膜异常区分开来。右房室口的“往返”血流模式可用于在超声心动图上区分UTVO与其他瓣膜发育异常。
