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对人心脏活检组织中肥大细胞的形态学和形态计量学分析。

Morphologic and morphometric analysis of the mast cells from human heart biopsies.

作者信息

Rydzyński K, Dalen H, Saetersdal T, Engedal H

出版信息

Agents Actions. 1987 Apr;20(3-4):288-90. doi: 10.1007/BF02074693.

DOI:10.1007/BF02074693
PMID:3604806
Abstract

We have examined mast cell morphology in human papillary muscles obtained from patients subjected to mitral valve replacement. Elongated, metachromatically staining mast cells were found in the connective tissue close to blood vessels and nerves. Electron microscopic examination showed that the most conspicuous features were cytoplasmic granules which displayed a crystalline internal structure and which were surrounded by perigranular membranes. They were composed of a number of coiled electron-dense layers (3 to 4 predominantly) which formed scrolls and gratings. Apart from the crystalline structure, all granules had a dark, uniform matrix. Measurements of crystalline structure periodicity indicated a unimodal distribution around a mean of 85.6 +/- 1.9 A.

摘要

我们已经检查了从接受二尖瓣置换术的患者获取的人乳头肌中的肥大细胞形态。在靠近血管和神经的结缔组织中发现了细长的、异染性染色的肥大细胞。电子显微镜检查显示,最显著的特征是细胞质颗粒,其呈现出晶体内部结构并被颗粒周膜包围。它们由许多盘绕的电子致密层(主要为3至4层)组成,这些层形成了卷轴和光栅。除了晶体结构外,所有颗粒都有一个深色、均匀的基质。晶体结构周期性的测量表明,在平均85.6 +/- 1.9埃周围呈单峰分布。

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本文引用的文献

1
Pinacyanol erthrosinate as a stain for mast cells.赤藓红 pinacyanol 作为肥大细胞的染色剂。
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2
Acid hydrolases and tryptase from secretory granules of dispersed human lung mast cells.来自人分散肺肥大细胞分泌颗粒的酸性水解酶和类胰蛋白酶。
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Secretion in dissociated human pulmonary mast cells. Evidence for solubilization of granule contents before discharge.人肺肥大细胞解离后的分泌。颗粒内容物在释放前溶解的证据。
Agents Actions. 1988 Apr;23(3-4):273-5. doi: 10.1007/BF02142562.
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Agents Actions. 1990 Apr;30(1-2):198-201. doi: 10.1007/BF01969037.
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The mast cell in normal human bronchus and lung.正常人类支气管和肺中的肥大细胞。
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A fine structure study of some cellular components in allergic reactions. 1. Degranulation of human mast cells in allergic asthma and perennial rhinitis.过敏反应中某些细胞成分的精细结构研究。1. 过敏性哮喘和常年性鼻炎中人类肥大细胞的脱颗粒作用。
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Isolation and characterization of human intestinal mucosal mast cells.人肠道黏膜肥大细胞的分离与鉴定
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In situ degranulation of human nasal mucosal mast cells: ultrastructural features and cell-cell associations.人鼻黏膜肥大细胞的原位脱颗粒:超微结构特征及细胞间关联
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