Department of Reproductive, Maternal, Newborn, and Child Health, Centre for Infectious Disease Research in Zambia, Lusaka, Zambia.
The Brown School, Washington University in St. Louis, St. Louis, Missouri, United States of America.
PLoS One. 2022 Sep 1;17(9):e0272444. doi: 10.1371/journal.pone.0272444. eCollection 2022.
Globally, complications due to preterm birth are the leading contributor to neonatal mortality, resulting in an estimated one million deaths annually. Kangaroo Mother Care (KMC) has been endorsed by the World Health Organisation as a low cost, safe, and effective intervention in reducing morbidity and mortality among preterm infants. The objective of this study was to describe the implementation of a KMC model among preterm infants and its impact on neonatal outcomes at a tertiary level hospital in Lusaka, Zambia.
We conducted a prospective descriptive study using data collected from the KMC room at the University Teaching Hospital between January 2016 and September 2017. Mothers and government nurses were trained in KMC. We monitored skin-to-skin and breastfeeding practices, weight at admission, discharge, and length of admission.
We enrolled 573 neonates into the study. Thirteen extremely low weight infants admitted to the KMC room had graduated to Group A (1,000g-1,499g) at discharge, with a median weight gain of 500g. Of the 419 very low weight neonates at admission, 290 remained in Group A while 129 improved to Group B (1,500g-2,499g), with a median weight gain of 280g. Among the 89 low weight neonates, 1 regressed to Group A, 77 remained in Group B, and 11 improved to Group C (≥2,500g), individually gaining a median of 100g. Of the seven normal weight neonates, 6 remained in Group C individually gaining a median of 100g, and 1 regressed to Group B. Among all infants enrolled, two (0.35%) died in the KMC room.
Based on the RE-AIM metrics, our results show that KMC is a feasible intervention that can improve neonatal outcomes among preterm infants in Zambia. The study findings show a promising, practical approach to scaling up KMC in Zambia.
The trial is registered under ClinicalTrials.gov under the following ID number: NCT03923023.
在全球范围内,早产并发症是导致新生儿死亡的主要原因,每年估计有 100 万人因此死亡。袋鼠式护理(KMC)已被世界卫生组织认可为一种低成本、安全且有效的干预措施,可降低早产儿的发病率和死亡率。本研究旨在描述赞比亚卢萨卡一家三级医院中早产婴儿 KMC 模式的实施情况及其对新生儿结局的影响。
我们进行了一项前瞻性描述性研究,使用 2016 年 1 月至 2017 年 9 月期间在大学教学医院 KMC 病房收集的数据。对母亲和政府护士进行 KMC 培训。我们监测了皮肤接触和母乳喂养的实施情况、入院时、出院时和住院时间的体重。
我们共纳入 573 名新生儿进行研究。13 名极低体重儿入住 KMC 病房,出院时已进入 A 组(1000-1499g),体重中位数增加了 500g。419 名极低体重儿入院时,290 名仍留在 A 组,129 名改善至 B 组(1500-2499g),体重中位数增加了 280g。在 89 名低体重儿中,1 名体重下降至 A 组,77 名留在 B 组,11 名体重增加至 C 组(≥2500g),体重中位数分别增加了 100g。7 名正常体重儿中,6 名体重增加至 C 组,体重中位数增加了 100g,1 名体重下降至 B 组。所有入组婴儿中,有 2 名(0.35%)在 KMC 病房死亡。
基于 RE-AIM 指标,我们的研究结果表明,KMC 是一种可行的干预措施,可以改善赞比亚早产儿的新生儿结局。研究结果表明,KMC 是一种很有前途的实用方法,可在赞比亚扩大规模。
该试验在 ClinicalTrials.gov 注册,以下是其注册号:NCT03923023。