Atmospheric Chemistry Department, Max Planck Institute for Chemistry, Mainz, Germany.
Department of Chemistry, University of California, Irvine, CA, USA.
Science. 2022 Sep 2;377(6610):1071-1077. doi: 10.1126/science.abn0340. Epub 2022 Sep 1.
Hydroxyl (OH) radicals are highly reactive species that can oxidize most pollutant gases. In this study, high concentrations of OH radicals were found when people were exposed to ozone in a climate-controlled chamber. OH concentrations calculated by two methods using measurements of total OH reactivity, speciated alkenes, and oxidation products were consistent with those obtained from a chemically explicit model. Key to establishing this human-induced oxidation field is 6-methyl-5-hepten-2-one (6-MHO), which forms when ozone reacts with the skin-oil squalene and subsequently generates OH efficiently through gas-phase reaction with ozone. A dynamic model was used to show the spatial extent of the human-generated OH oxidation field and its dependency on ozone influx through ventilation. This finding has implications for the oxidation, lifetime, and perception of chemicals indoors and, ultimately, human health.
羟基（OH）自由基是高度反应性的物种，可以氧化大多数污染物气体。在这项研究中，当人们在气候控制室内暴露于臭氧时，发现了高浓度的 OH 自由基。使用总 OH 反应性、特定烯烃和氧化产物测量值的两种方法计算的 OH 浓度与从化学显式模型获得的浓度一致。建立这个人为诱导氧化场的关键是 6-甲基-5-庚烯-2-酮（6-MHO），当臭氧与皮脂中的角鲨烯反应时会形成 6-MHO，随后通过与臭氧的气相反应有效地生成 OH。使用动态模型展示了人为产生的 OH 氧化场的空间范围及其对通风通过臭氧流入的依赖性。这一发现对室内化学物质的氧化、寿命和感知，最终对人类健康都有影响。
