Chirurgia (Bucur). 2022 Jun;117(3):317-327. doi: 10.21614/chirurgia.2719.
Abstract COVID-19 (Coronavirus-19 disease), a new clinical entity caused by SARS-COV-2 infection, could explain the physiopathology of cervicothoracic air collections (pneumothorax, pneumomediastinum, and subcutaneous emphysema). We conducted an 8-months retrospective analysis of a single-center SARS-CoV-2 cases associating pneumothorax, pneumomediastinum, and subcutaneous emphysema, either alone or combined. All non-intubated patients with the complications cited above had a favorable outcome after pleural drainage, percutaneous drainage, and/or conservative treatment, while the intubated patients, with multiple comorbidities, have had an unfavorable outcome, regardless the chosen treatment. Pleural drainage was used for pneumothorax cases; pneumomediastinum with subcutaneous emphysema required insertion of subcutaneous needles or angio-catheters with manual decompressive massage. Conservative methods of treatment were used for patients with pneumomediastinum and medium or severe respiratory disfunction. Etiopathogenic classification of pneumothorax should include SARS-CoV-2 infection as a possible cause of secondary spontaneous pneumothorax due to COVID-19 pneumonia. Survival rate after the occurrence of these complications was small (18,75%), 4 of the patients were cured, 2 had a favorable outcome and 26 have died. Pleural drainage which is mandatory to do for patients with pneumothorax complication in COVID -19 pneumonia, doesn't change the prognosis for those with severe affecting lungs, because the prolonged ventilation and the other comorbidities have led to death in most of these cases.
摘要 COVID-19(SARS-CoV-2 病毒引起的冠状病毒病)可解释由 SARS-COV-2 感染引起的颈胸部空气积聚(气胸、纵隔气肿和皮下气肿)的病理生理学。我们对一家中心的 SARS-CoV-2 病例进行了 8 个月的回顾性分析,这些病例单独或联合出现气胸、纵隔气肿和皮下气肿。所有上述并发症的非插管患者在进行胸腔引流、经皮引流和/或保守治疗后均有良好的结局,而伴有多种合并症的插管患者无论选择何种治疗方法均预后不良。气胸病例采用胸腔引流;纵隔气肿伴皮下气肿需要插入皮下针或血管导管,并进行手动减压按摩。对于纵隔气肿和中重度呼吸功能障碍的患者,采用保守治疗方法。气胸的病因分类应将 SARS-CoV-2 感染作为 COVID-19 肺炎引起的继发性自发性气胸的可能原因之一。这些并发症发生后的存活率较低(18.75%),4 例患者治愈,2 例患者病情好转,26 例患者死亡。对于 COVID-19 肺炎合并气胸并发症的患者,必须进行胸腔引流,但这并不能改变那些肺部严重受累患者的预后,因为长时间通气和其他合并症导致这些患者中的大多数死亡。