Department of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA; Department of Physical Therapy, University of Alabama at Birmingham, Birmingham, AL, USA.
Department of Physical Therapy, University of Alabama at Birmingham, Birmingham, AL, USA.
Sleep Med. 2022 Dec;100:120-127. doi: 10.1016/j.sleep.2022.08.001. Epub 2022 Aug 14.
OBJECTIVE/BACKGROUND: The present study examined the associations among physical activity during different times of the day(i.e., morning, midday,evening) and days of the week(i.e., weekdays, weekend days) with restless legs syndrome(RLS) severity and sleep quality in adults with multiple sclerosis(MS).
PATIENTS/METHODS: Participants(N = 39) completed the International Restless Legs Syndrome Study Group Scale and the Pittsburgh Sleep Quality Index as measures of RLS severity and global sleep quality, respectively, and wore an ActiGraph GT3X + on the non-dominant hip for seven days for measuring physical activity(i.e., light physical activity[LPA], moderate-to-vigorous physical activity[MVPA], and steps).
There was a significant effect of time of day wherein participants had more midday activity compared with morning or evening for LPA, MVPA, and steps; there was no effect of day of the week. Spearman's rho correlations across the week indicated higher evening LPA, evening steps, and overall daily steps (ρ = -0.42,ρ = -0.51,ρ = -0.40,respectively) were associated with lower RLS severity. Similar associations were demonstrated for weekdays(ρ = -0.39,ρ = -0.50,ρ = -0.41,respectively) and weekend days(ρ = -0.44,ρ = -0.51,ρ = -0.39,respectively). Higher evening MVPA on weekend days(ρ = -0.42) was associated with lower RLS severity. Higher morning and overall daily LPA(ρ = 0.34,ρ = 0.33,respecitvely) were associated with worse sleep quality. Similar associations were demonstrated on weekdays(ρ = 0.33,ρ = 0.37,respectively) and more evening MVPA(ρ = 0.32) was associated with worse sleep quality. On weekend days, more morning MVPA(ρ = 0.42) was associated with worse sleep quality.
Our results suggest that undertaking physical activity, particularly LPA and steps, in evenings may be important for managing symptoms of RLS without worsening sleep quality.
目的/背景：本研究调查了白天不同时段（即上午、中午、晚上）和一周中不同日子（即工作日、周末）的身体活动与多发性硬化症（MS）成人的不安腿综合征（RLS）严重程度和睡眠质量之间的关联。
患者/方法：39 名参与者完成了国际不安腿综合征研究组量表和匹兹堡睡眠质量指数，分别作为 RLS 严重程度和整体睡眠质量的衡量标准，并在非优势髋部佩戴 ActiGraph GT3X+七天，以测量身体活动（即轻体力活动[LPA]、中到剧烈体力活动[MVPA]和步数）。
时间存在显著影响，即与上午或晚上相比，参与者中午的活动更多，无论是 LPA、MVPA 还是步数；而星期几没有影响。一周内的斯皮尔曼 rho 相关表明，傍晚的 LPA、傍晚的步数和全天的总步数（ρ=-0.42、ρ=-0.51、ρ=-0.40，分别）与 RLS 严重程度较低有关。类似的关联也存在于工作日（ρ=-0.39、ρ=-0.50、ρ=-0.41，分别）和周末（ρ=-0.44、ρ=-0.51、ρ=-0.39，分别）。周末晚上的 MVPA 较高（ρ=-0.42）与 RLS 严重程度较低有关。周末早上和全天 LPA 较高（ρ=0.34、ρ=0.33，分别）与睡眠质量较差有关。类似的关联也存在于工作日（ρ=0.33、ρ=0.37，分别）和更多的傍晚 MVPA（ρ=0.32）与睡眠质量较差有关。在周末，更多的早晨 MVPA（ρ=0.42）与睡眠质量较差有关。
我们的研究结果表明，在晚上进行身体活动，特别是 LPA 和步数，可能对管理 RLS 症状很重要，而不会恶化睡眠质量。
