Department of Physical Therapy, University of Alabama at Birmingham, AL, USA(1).
Department of Physical Therapy, University of Alabama at Birmingham, AL, USA(1).
J Neurol Sci. 2019 Dec 15;407:116531. doi: 10.1016/j.jns.2019.116531. Epub 2019 Oct 12.
The present study examined the relationships among parameters (i.e., volume and pattern) of physical activity and sedentary behavior with the presence and severity of restless legs syndrome(RLS) in adults with multiple sclerosis(MS). Participants with MS (N = 253) wore an accelerometer for a 7-day period and completed the Cambridge-Hopkins Restless Legs Syndrome Questionnaire, the International Restless Legs Syndrome Study Group Scale (IRLS), and the Patient Determined Disease Steps scale. Sixty-six (26%) persons with MS had RLS (MS + RLS). There were no differences between the MS + RLS and MS group for parameters of physical activity or sedentary behavior. Among participants with IRLS scores in the mild range (n = 26), more time spent in light physical activity (r = 0.39), fewer sedentary bouts per day (r = 0.55), less time in sedentary bouts per day (r = 0.51), and fewer breaks in sedentary time per day (r = 0.57) were associated with lower RLS severity. This study represents the first step toward recognizing a relationship between physical activity, patterns of sedentary behavior, and RLS severity in MS and these results suggest that light physical activity and the pattern of sedentary behavior may be important targets for prospective behavioral interventions that target the management of RLS in persons with MS who have mild RLS severity.
本研究探讨了成年人多发性硬化症（MS）患者的体力活动和久坐行为的参数（即量和模式）与不安腿综合征（RLS）的存在和严重程度之间的关系。患有 MS 的参与者（N=253）佩戴加速度计 7 天，并完成了剑桥-霍普金斯不安腿综合征问卷、国际不安腿综合征研究组量表（IRLS）和患者确定疾病阶段量表。66 名 MS 患者（26%）患有 RLS（MS+RLS）。MS+RLS 组和 MS 组在体力活动或久坐行为的参数方面没有差异。在 IRLS 评分处于轻度范围的参与者中（n=26），更多的时间进行轻度体力活动（r=0.39）、每天更少的久坐时间（r=0.55）、每天更少的久坐时间（r=0.51）和每天更少的久坐时间（r=0.57）与较低的 RLS 严重程度相关。这项研究代表了朝着认识 MS 中体力活动、久坐行为模式与 RLS 严重程度之间关系迈出的第一步，这些结果表明，轻度体力活动和久坐行为模式可能是针对具有轻度 RLS 严重程度的 RLS 管理的前瞻性行为干预的重要目标。
