胸膜剥脱术和高热胸腔内化疗治疗假黏液瘤。
Pleural decortication and hyperthermic intrathoracic chemotherapy for pseudomyxoma.
机构信息
Department of Thoracic Surgery, University Hospitals Leuven, Leuven, Belgium.
Department of Chronic Diseases and Metabolism, Laboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), KU Leuven, Leuven, Belgium.
出版信息
Int J Hyperthermia. 2022;39(1):1153-1157. doi: 10.1080/02656736.2022.2104938.
Pleural dissemination of pseudomyxoma peritonei (PMP) is an extremely rare diagnosis, for which no standard therapy is available. We describe the successful treatment of a 67-year-old male diagnosed with left-sided intrapleural dissemination of PMP (low-grade appendiceal mucinous neoplasm), 2 years after treatment of abdominal PMP with cytoreductive surgery (CRS) and hyperthermic intra-peritoneal chemotherapy. Treatment consisted of extended pleural decortication (ePD) and oxaliplatin-based hyperthermic intrathoracic chemotherapy (HITHOC). The patient is doing well without complications or signs of recurrence, 26 months after thoracic surgery. ePD in combination with HITHOC is a valuable treatment for thoracic PMP.
腹膜假性黏液瘤（PMP）的胸膜播散是一种极为罕见的诊断，目前尚无标准的治疗方法。我们描述了一例成功治疗的病例，一名 67 岁男性，在接受腹部 PMP 的细胞减灭术（CRS）和腹腔热灌注化疗（HIPEC）治疗 2 年后，诊断为左侧胸膜内播散性 PMP（低级别阑尾黏液性肿瘤）。治疗包括广泛的胸膜剥脱术（ePD）和奥沙利铂为基础的胸腔内热化疗（HITHOC）。胸外科手术后 26 个月，患者无并发症或复发迹象，恢复良好。ePD 联合 HITHOC 是治疗胸膜 PMP 的有效方法。
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