Department of Thoracic Surgery, University Hospitals Leuven, Leuven, Belgium.
Department of Chronic Diseases and Metabolism, Laboratory of Respiratory Diseases and Thoracic Surgery (BREATHE), KU Leuven, Leuven, Belgium.
Int J Hyperthermia. 2022;39(1):1153-1157. doi: 10.1080/02656736.2022.2104938.
Pleural dissemination of pseudomyxoma peritonei (PMP) is an extremely rare diagnosis, for which no standard therapy is available. We describe the successful treatment of a 67-year-old male diagnosed with left-sided intrapleural dissemination of PMP (low-grade appendiceal mucinous neoplasm), 2 years after treatment of abdominal PMP with cytoreductive surgery (CRS) and hyperthermic intra-peritoneal chemotherapy. Treatment consisted of extended pleural decortication (ePD) and oxaliplatin-based hyperthermic intrathoracic chemotherapy (HITHOC). The patient is doing well without complications or signs of recurrence, 26 months after thoracic surgery. ePD in combination with HITHOC is a valuable treatment for thoracic PMP.
腹膜假性黏液瘤（PMP）的胸膜播散是一种极为罕见的诊断，目前尚无标准的治疗方法。我们描述了一例成功治疗的病例，一名 67 岁男性，在接受腹部 PMP 的细胞减灭术（CRS）和腹腔热灌注化疗（HIPEC）治疗 2 年后，诊断为左侧胸膜内播散性 PMP（低级别阑尾黏液性肿瘤）。治疗包括广泛的胸膜剥脱术（ePD）和奥沙利铂为基础的胸腔内热化疗（HITHOC）。胸外科手术后 26 个月，患者无并发症或复发迹象，恢复良好。ePD 联合 HITHOC 是治疗胸膜 PMP 的有效方法。
