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改良5项衰弱指数预测择期颈椎、胸椎和腰椎后路脊柱融合手术后并发症及死亡率的效用:来自美国外科医师学会国家外科质量改进计划(ACS-NSQIP)数据库的多中心分析

Utility of the Modified 5-Items Frailty Index to Predict Complications and Mortality After Elective Cervical, Thoracic and Lumbar Posterior Spine Fusion Surgery: Multicentric Analysis From ACS-NSQIP Database.

作者信息

Camino-Willhuber Gaston, Choi Jeffrey, Holc Fernando, Oyadomari Sarah, Guiroy Alfredo, Bow Hansen, Hashmi Sohaib, Oh Michael, Bhatia Nitin, Lee Yu-Po

机构信息

Orthopaedic and Traumatology Department, Institute of Orthopedics "Carlos E. Ottolenghi," Hospital Italiano de Buenos Aires, Buenos Aires, Argentina.

Department of Orthopaedics, University of California at Irvine, Orange, CA, USA.

出版信息

Global Spine J. 2024 Apr;14(3):839-845. doi: 10.1177/21925682221124101. Epub 2022 Sep 1.

Abstract

STUDY DESIGN

Retrospective review of multicentric data.

OBJECTIVES

The modified 5-item frailty index is a relatively new tool to assess the post-operative complication risks. It has been recently shown a good predictive value after posterior lumbar fusion. We aimed to compare the predictive value of the modified 5-item frailty index in cervical, thoracic and lumbar surgery.

METHODS

The American College of Surgeons - National Surgical Quality Improvement Program (ACS-NSQIP) Database 2015-2020 was used to identify patients who underwent elective posterior cervical, thoracic, or lumbar fusion surgeries for degenerative conditions. The mFI-5 score was calculated based on the presence of 5 co-morbidities: congestive heart failure within 30 days prior to surgery, insulin-dependent or noninsulin-dependent diabetes mellitus, chronic obstructive pulmonary disease or pneumonia, partially dependent or totally dependent functional health status at time of surgery, and hypertension requiring medication. Multivariate analysis was used to assess the independent impact of increasing mFI-5 score on the postoperative morbidity while controlling for baseline clinical characteristics.

RESULTS

53 252 patients were included with the mean age of 64.2 ± 7.2. 7946 suffered medical complications (14.9%), 1565 had surgical complications (2.9%), and 3385 were readmitted (6.3%), 363 died (.68%) within 30 days postoperative (6.3%). The mFI-5 items score was significantly associated with higher rates of complications, readmission, and mortality in cervical, thoracic, and lumbar posterior fusion surgery.

CONCLUSION

The modified 5-item frailty score is a reliable tool to predict complications, readmission, and mortality in patients planned for elective posterior spinal fusion surgery.

摘要

研究设计

多中心数据的回顾性分析。

目的

改良的5项衰弱指数是评估术后并发症风险的一种相对较新的工具。最近研究表明其在腰椎后路融合术后具有良好的预测价值。我们旨在比较改良的5项衰弱指数在颈椎、胸椎和腰椎手术中的预测价值。

方法

利用美国外科医师学会-国家外科质量改进计划(ACS-NSQIP)2015-2020数据库,识别因退行性疾病接受择期颈椎、胸椎或腰椎后路融合手术的患者。基于5种合并症计算mFI-5评分:术前30天内的充血性心力衰竭、胰岛素依赖型或非胰岛素依赖型糖尿病、慢性阻塞性肺疾病或肺炎、手术时部分依赖或完全依赖的功能健康状态,以及需要药物治疗的高血压。在控制基线临床特征的同时,采用多变量分析评估mFI-5评分升高对术后发病率的独立影响。

结果

纳入53252例患者,平均年龄64.2±7.2岁。7946例出现医疗并发症(14.9%),1565例出现手术并发症(2.9%),3385例再次入院(6.3%),363例(0.68%)在术后30天内死亡(6.3%)。mFI-5项目评分与颈椎、胸椎和腰椎后路融合手术中较高的并发症、再次入院和死亡率显著相关。

结论

改良的5项衰弱评分是预测计划进行择期后路脊柱融合手术患者并发症、再次入院和死亡率的可靠工具。

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