衰弱指数作为脊髓型颈椎病患者椎板成形术后颈椎生理前凸丢失的预测指标。
Frailty index as predictors of loss of cervical lordosis following laminoplasty in patients with cervical spondylotic myelopathy.
作者信息
Kann Michael Ryan, Ruiz-Cardozo Miguel A, Barot Karma, Joseph Karan, Bui Tim, Yakdan Salim, Brehm Samuel, Trevino Gabriel, Carey-Ewend Abigail, Olufawo Michael, Yahanda Alexander Thomas, Pennicooke Brenton, Molina Camilo A
机构信息
Department of Neurological Surgery, University of Pittsburgh School of Medicine, Pittsburgh, PA.
Deparment of Neurological Surgery, Washington University School of Medicine, Saint Louis, MO, USA.
出版信息
J Craniovertebr Junction Spine. 2025 Apr-Jun;16(2):148-156. doi: 10.4103/jcvjs.jcvjs_204_24. Epub 2025 Jul 3.
BACKGROUND
Postlaminoplasty kyphotic deformity (PKD) is a complication affecting roughly 20% of patients undergoing cervical laminoplasty. Identification of preoperative risk factors for PKD could allow surgeons to adapt treatment plans to reduce PKD.
OBJECTIVE
The aim of this study was to investigate the ability of the Charlson Comorbidity Index (CCI), 5-item Modified Frailty Index (5i-mFi), and Administrative Risk Analysis Index (RAI-A) to predict for the development of PKD in patients with cervical spondylotic myelopathy (CSM) undergoing laminoplasty.
MATERIALS AND METHODS
We retrospectively reviewed CSM patients who underwent laminoplasty at an academic tertiary care center between January 1, 2016, and January 30, 2022, and had a complete set of anterolateral cervical X-rays at 1-year follow-up. Angular kyphosis was defined as the loss of cervical lordosis by more than - 10° after surgery when measuring the difference between pre- and post-operative C2-7 Cobb angles. Regression and receiver operating characteristic (ROC) curve analysis were used to assess the ability of the frailty assessments to predict for PKD.
RESULTS
Seventy-six CMS patients were eligible, 11.8% of which developed PKD. The cohort consisted of 54 males and 22 females with a mean age of 59.5 years and body mass index of 29.2 kg/m. No CCI, 59-mFi, or RAI-A frailty subgroup was associated with kyphotic development and ROC curve analysis showed that neither CCI (P = 0.81), 5i-mFi (P = 0.59), nor RAI-A (P = 0.63) predicted for PKD. None of these assessments were a superior prognosticator of PKD.
CONCLUSION
CCI, 5i-mFi, and RAI-A frailty assessments were not associated with the development of PKD in CSM patients.
背景
椎板成形术后后凸畸形(PKD)是一种并发症,约20%接受颈椎椎板成形术的患者会受到影响。识别PKD的术前危险因素可使外科医生调整治疗方案以减少PKD。
目的
本研究的目的是调查Charlson合并症指数(CCI)、5项改良衰弱指数(5i-mFi)和行政风险分析指数(RAI-A)预测接受椎板成形术的脊髓型颈椎病(CSM)患者发生PKD的能力。
材料与方法
我们回顾性分析了2016年1月1日至2022年1月30日期间在一家学术性三级医疗中心接受椎板成形术且在1年随访时有完整颈椎前外侧X线片的CSM患者。角状后凸畸形定义为测量术后C2-7 Cobb角与术前差值时,术后颈椎前凸丢失超过-10°。采用回归分析和受试者工作特征(ROC)曲线分析来评估衰弱评估预测PKD的能力。
结果
76例CMS患者符合条件,其中11.8%发生了PKD。该队列包括54名男性和22名女性,平均年龄59.5岁,体重指数29.2 kg/m。没有CCI、59-mFi或RAI-A衰弱亚组与后凸畸形发展相关,ROC曲线分析表明CCI(P = 0.81)、5i-mFi(P = 0.59)和RAI-A(P = 0.63)均不能预测PKD。这些评估均不是PKD的优越预后指标。
结论
CCI、5i-mFi和RAI-A衰弱评估与CSM患者PKD的发生无关。
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