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肠道病毒组:酒精性和非酒精性肝病的重要研究方向。

Intestinal virome: An important research direction for alcoholic and nonalcoholic liver diseases.

机构信息

Department of Gastroenterology, The First Affiliated Hospital of China Medical University, Shenyang 110001, Liaoning Province, China.

出版信息

World J Gastroenterol. 2022 Jul 14;28(26):3279-3281. doi: 10.3748/wjg.v28.i26.3279.

Abstract

In recent years, the interaction between the gut microflora and liver diseases has attracted much attention. The intestinal microflora is composed of bacteria, archaea, fungi and viruses. There are few studies on the intestinal virome, and whether it has a causal relationship with bacterial changes in the gut is still unclear. However, it is undeniable that the intestinal virome is also a very important portion of the blueprint for the development of liver diseases and the diagnosis and therapeutic modalities in the future.

摘要

近年来,肠道微生物群与肝脏疾病的相互作用引起了广泛关注。肠道微生物群由细菌、古菌、真菌和病毒组成。目前关于肠道病毒组的研究较少,其与肠道细菌变化是否存在因果关系尚不清楚。然而,不可否认的是,肠道病毒组也是肝脏疾病发展以及未来诊断和治疗模式的重要蓝图组成部分之一。

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J Microbiol. 2021 Mar;59(3):292-297. doi: 10.1007/s12275-021-1004-0. Epub 2021 Feb 23.
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Intestinal Virome in Patients With Alcoholic Hepatitis.酒精性肝炎患者的肠道病毒组。
Hepatology. 2020 Dec;72(6):2182-2196. doi: 10.1002/hep.31459. Epub 2020 Oct 10.

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