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越南中部一家三级儿科中心儿童细菌性脑膜炎的主要临床和实验室特征:经验总结

Main Clinical and Laboratory Features of Children with Bacterial Meningitis: Experience from a Tertiary Paediatric Centre in Central Vietnam.

作者信息

Nguyen-Huu Chau Duc, Bui-Binh-Bao Son, Tran Kiem Hao, Mai Van Tuan, Nguyen-Thi Diem Chi, Tran-Thi Hanh Chan, Nguyen-Duy-Nam Anh, To Phuc, Ton-Nu Van Anh

机构信息

Department of Pediatrics, Hue University of Medicine and Pharmacy, Hue University, Hue City, Vietnam.

Pediatric Center, Hue Central Hospital, Hue City, Vietnam.

出版信息

Pediatric Health Med Ther. 2022 Aug 26;13:289-295. doi: 10.2147/PHMT.S371914. eCollection 2022.

DOI:10.2147/PHMT.S371914
PMID:36051354
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9427117/
Abstract

OBJECTIVE

Our study aimed to summarize symptoms and laboratory findings of bacterial meningitis at a Vietnam tertiary care hospital.

METHODS

We performed a retrospective study and enrolled 33 children diagnosed with bacterial meningitis admitted at the Pediatric Center, Hue Central Hospital, between January 2019 and July 2021.

RESULTS

Only 24.2% (8 out of 33) cases can determine etiology of bacterial meningitis. was the most common pathogen. The mortality in this study was 12.1%. The most commn symptoms were fever (93.9%) and vomiting (60.6%). Loss of consciousness and poor appetite were predominant among patients who died (75%); seizures and local paralysis accounted for a half. For cerebrospinal fluid (CSF), the cloudy or turbid color was the most common in bacterial meningitis (54.5%), CSF leucocytes in a half of patients were greater than 500 cells/mm (48.5%). CSF white blood cells count was higher among children who died.

CONCLUSION

was the most common pathogen. Fever, vomiting, loss of consciousness, local paralysis, and increased leucocytes, neutrophils of CSF were more common in severe cases.

摘要

目的

我们的研究旨在总结越南一家三级护理医院细菌性脑膜炎的症状和实验室检查结果。

方法

我们进行了一项回顾性研究,纳入了2019年1月至2021年7月期间在顺化中央医院儿科中心收治的33例诊断为细菌性脑膜炎的儿童。

结果

仅24.2%(33例中的8例)病例能够确定细菌性脑膜炎的病因。 是最常见的病原体。本研究中的死亡率为12.1%。最常见的症状是发热(93.9%)和呕吐(60.6%)。意识丧失和食欲不振在死亡患者中占主导(75%);癫痫发作和局部麻痹占一半。对于脑脊液(CSF),细菌性脑膜炎中最常见的是浑浊或混浊的颜色(54.5%),一半患者的脑脊液白细胞大于500个细胞/mm(48.5%)。死亡儿童的脑脊液白细胞计数更高。

结论

是最常见的病原体。发热、呕吐、意识丧失、局部麻痹以及脑脊液白细胞、中性粒细胞增多在重症病例中更为常见。

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