Salih Khalid Hama, Najmadden Zana Baqi, Ahmed Bahadin Qader, Ismael Pishdar Abdullah, Kareem Kaiwan H, Abdulqadir Lana Diyar, Sabir Roza M, Abdalla Basta J, Qadir Binay A, Mohammed Razhan M, Karim Ali Salih
University of Sulaimani, Sulaimani, Kurdistan, Iraq.
University of Halabja, Halabja, Kurdistan Region, Iraq.
Glob Pediatr Health. 2024 Nov 6;11:2333794X241293948. doi: 10.1177/2333794X241293948. eCollection 2024.
. To determine clinical presentations and laboratory findings of meningitis outbreak among children in 2023 in Iraq. . the demographic data (gender, age, symptoms, and disease transmission among family members) were collected from child patients, who were admitted to Halabja and Sulaimania pediatric teaching hospital in the period of 15 March 2023 to 1st of August, 2023. The blood and cerebrospinal fluid (CSF) specimens were collected for hematological, biochemical, microscopic, and microbiological examinations, including culturing and FilmArray meningitis/encephalitis panel. . The population studied were 170 children between 1 and 18 years old, Males were 110 (64.7%), and females were 60 (35.3%). Children between 5 and 10 years old had the highest frequency, whereas only 2 children were <1 year. Clinical symptoms were fever in 100%, followed by headache, vomiting, convulsion, photophobia, and lethargy (79%, 12%, 3%, 3%, 2%) respectively. CSF parameters were: 38.8% of them had >1000 leucocytes/µ, followed by 31.2% for those who had <300 cells/µ, differential CSF leucocytes, 82.4% were monocytes, and sugar was normal at 84.1%. while protein was <40 mg/d in 55.9% of them. . Meningitis outbreak due to enterovirus was recorded, and age predilection and clinical presentation refer to different serotypes. Further work is needed to define the species and serotypes of the virus and define the environmental source of the virus.
确定2023年伊拉克儿童脑膜炎暴发的临床表现和实验室检查结果。收集了2023年3月15日至8月1日期间入住哈拉布贾和苏莱曼尼亚儿科教学医院的儿童患者的人口统计学数据（性别、年龄、症状以及家庭成员之间的疾病传播情况）。采集血液和脑脊液（CSF）样本进行血液学、生化、显微镜和微生物学检查，包括培养和FilmArray脑膜炎/脑炎检测板检测。研究对象为170名1至18岁的儿童，其中男性110名（64.7%），女性60名（35.3%）。5至10岁的儿童发病率最高，而1岁以下的儿童仅有2名。临床症状方面，100%的患儿有发热症状，其次分别是头痛、呕吐、惊厥、畏光和嗜睡（发生率分别为79%、12%、3%、3%、2%）。脑脊液参数如下：38.8%的患儿白细胞计数>1000/µ，31.2%的患儿白细胞计数<300/µ，脑脊液白细胞分类中82.4%为单核细胞，84.1%的患儿血糖正常，55.9%的患儿蛋白质含量<40mg/d。记录到由肠道病毒引起的脑膜炎暴发，年龄偏好和临床表现因不同血清型而异。需要进一步开展工作来确定病毒的种类和血清型，并明确病毒的环境来源。
