Hecht Silke, Michaels Jennifer R, Simon Heather
Department of Small Animal Clinical Sciences, University of Tennessee, Knoxville, TN, United States.
Department of Neurology and Neurosurgery, Angell Animal Medical Center, Boston, MA, United States.
Front Vet Sci. 2022 Aug 16;9:966853. doi: 10.3389/fvets.2022.966853. eCollection 2022.
Blastomycosis is a systemic mycotic infection caused by dimorphic fungi. The disease is rare in cats, and reports on imaging findings with central nervous system (CNS) involvement are limited. Magnetic resonance imaging (MRI) was performed antemortem in three feline patients. Imaging findings that may allow prioritization of intracranial blastomycosis over other differential diagnoses included focal or multifocal intra-axial mass lesions with dural contact, lesion hypointensity on T2-weighted images and diffusion-weighted imaging/apparent diffusion coefficient map (DWI/ADC), strong and homogeneous contrast enhancement of the lesion(s), concurrent meningeal enhancement, marked perilesional edema and mass-effect, and ocular abnormalities. One cat was managed successfully and had a recurrence of CNS blastomycosis more than 4.5 years after the initial diagnosis. Repeat MRI at that point revealed both new and persistent (chronic) abnormalities.
芽生菌病是一种由双相真菌引起的全身性真菌感染。该病在猫中罕见，关于中枢神经系统（CNS）受累的影像学表现的报道有限。对三只猫科动物患者在生前进行了磁共振成像（MRI）检查。可能有助于将颅内芽生菌病优先于其他鉴别诊断的影像学表现包括与硬脑膜接触的局灶性或多灶性轴内肿块病变、T2加权图像和扩散加权成像/表观扩散系数图（DWI/ADC）上的病变低信号、病变的强烈且均匀的对比增强、并发的脑膜增强、明显的病变周围水肿和占位效应以及眼部异常。一只猫成功接受治疗，在初次诊断后超过4.5年出现中枢神经系统芽生菌病复发。此时重复MRI显示既有新的异常也有持续（慢性）异常。
